George Lazaros
National and Kapodistrian University of Athens
Internal medicineEtiologySurgeryCardiologyIntensive care medicineArterial stiffnessHeart failureCoronary artery diseaseCardiac tamponadeDiseaseAtrial fibrillationMEDLINEAcute pericarditisPericarditisPericardial effusionAnakinraIn patientMyocardial infarctionMedicineBlood pressure
200Publications
24H-index
1,484Citations
Publications 207
Newest
#1George Lazaros (UoA: National and Kapodistrian University of Athens)H-Index: 24
#2Costas Tsioufis (UoA: National and Kapodistrian University of Athens)H-Index: 47
Last. Charalambos Vlachopoulos (UoA: National and Kapodistrian University of Athens)H-Index: 73
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#1George Lazaros (UoA: National and Kapodistrian University of Athens)H-Index: 24
#2Cleo Anastassopoulou (UoA: National and Kapodistrian University of Athens)H-Index: 21
Last. Costas Tsioufis (UoA: National and Kapodistrian University of Athens)H-Index: 47
view all 10 authors...
Abstract null null Background null COVID-19 vaccines were efficacious and safe in clinical trials. We report nine events of acute pericarditis (AP) in eight patients following COVID-19 vaccination with BNT162b2 (6/9), AZD1222 (2/9) and mRNA-1273 (1/9). null null null Methods null All patients were referred for AP temporally linked with COVID-19 vaccination. Chest pain was the most common clinical manifestation. Alternative etiologies were excluded upon thorough diagnostic work up. AP diagnosis w...
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#1Massimo ImazioH-Index: 66
#2George LazarosH-Index: 24
Last. Antonio Brucato (University of Milan)H-Index: 65
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Anti-interleukin (IL)-1 agents have been developed for the treatment of autoinflammatory diseases characterized by overproduction of IL-1. Idiopathic recurrent pericarditis with inflammatory phenotype (fever, leukocytosis, and elevation of C-reactive protein) has similar features and responds well to this treatment. At present, in Italy, prescription of anakinra is possible for idiopathic recurrent pericarditis with corticosteroid dependence and colchicine resistance. Anakinra is a recombinant a...
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#1Massimo ImazioH-Index: 66
#2George Lazaros (UoA: National and Kapodistrian University of Athens)H-Index: 24
Last. Allan L. Klein (Cleveland Clinic)H-Index: 80
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Anti-interleukin (IL)-1 agents have been developed for the treatment of autoinflammatory and rheumatic conditions, where overproduction of IL-1 is an important pathophysiologic process. IL-1α and IL-1β are the most studied members of the IL-1 family of cytokines and have the strongest proinflammatory effects. A naturally occurring antagonist (IL-1Ra) mitigates their proinflammatory effects. Overproduction of both IL-1α (released by inflamed/damaged pericardial cells) and IL-1β (released by infla...
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#1George Lazaros (UoA: National and Kapodistrian University of Athens)H-Index: 24
#2Allan L. Klein (Cleveland Clinic)H-Index: 80
Last. Cleo Anastassopoulou (UoA: National and Kapodistrian University of Athens)H-Index: 21
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#1George Lazaros (UoA: National and Kapodistrian University of Athens)H-Index: 24
#2Emilia Lazarou (UoA: National and Kapodistrian University of Athens)H-Index: 6
Last. Konstantinos Tsioufis (UoA: National and Kapodistrian University of Athens)H-Index: 26
view all 5 authors...
The main pericardial syndromes include acute and recurrent pericarditis, constrictive pericarditis and chronic pericardial effusion in the absence of overt inflammation. Despite recent advances in pericardial syndromes, certain clinical scenarios depict remarkable peculiarities and their management is often challenging for the clinician. Acute pericarditis is the most common pericardial disease and in most instances is accompanied by pericardial effusion. On the other hand, pericardial effusion ...
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#1Evangelos Oikonomou (UoA: National and Kapodistrian University of Athens)H-Index: 32
#2George Lazaros (UoA: National and Kapodistrian University of Athens)H-Index: 24
Last. M.N. Assimakopoulos (UoA: National and Kapodistrian University of Athens)H-Index: 23
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Abstract null null Background null Air pollution is a well-described environmental factor with evidence suggesting a firm association with cardiovascular diseases. The purpose of this study was to determine the association of exposure to gaseous air pollutants on atherosclerosis burden. null null null Methods null 1955 inhabitants of the Corinthia region, aged 40 years or older, underwent clinical and biochemical assessment as well as carotid ultrasonography to evaluate carotid intima-media thic...
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Current guidelines on the management of pericardial diseases suggest to identify high-risk features associated with an increased risk of non-idiopathic aetiology and complications. The aim of this study is to evaluate a “pericarditis score” to assess potential complicated pericarditis in order to facilitate initial clinical triage. Consecutive patients with pericarditis were included in a prospective cohort study from January 2017 to December 2018. Complicated pericarditis was defined as pericar...
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#1George Lazaros (UoA: National and Kapodistrian University of Athens)H-Index: 24
#2Dimitrios Tousoulis (UoA: National and Kapodistrian University of Athens)H-Index: 47
Last. Dimitrios Vassilopoulos (UoA: National and Kapodistrian University of Athens)H-Index: 36
view all 3 authors...
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#1George Lazaros (UoA: National and Kapodistrian University of Athens)H-Index: 24
#2Charalambos Vlachopoulos (UoA: National and Kapodistrian University of Athens)H-Index: 73
Last. Konstantinos Tsioufis (UoA: National and Kapodistrian University of Athens)H-Index: 26
view all 4 authors...
PURPOSE OF REVIEW Pericardial effusion is a challenging pericardial syndrome and a cause of serious concern for physicians and patients due to its potential progression to life-threatening cardiac tamponade. In this review, we summarize the contemporary evidence of the etiology; diagnostic work-up, with particular emphasis on the contribution of multimodality imaging; therapeutic options; and short- and long-term outcomes of these patients. RECENT FINDINGS In recent years, an important piece of ...
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