Gulisa Turashvili
University of Toronto
CancerGermline mutationPathologyOncologySerous fluidTranscriptomeGene expression profilingTissue microarrayImmunohistochemistryEndometrial cancerCarcinomaOvaryLymph nodeAdenocarcinomaMutationCancer researchBreast cancerGeneticsMedicineBiology
94Publications
27H-index
11.7kCitations
Publications 95
Newest
#1Roman E. Zyla (U of T: University of Toronto)H-Index: 1
#2Tracy Graham (Sunnybrook Health Sciences Centre)H-Index: 5
Last. Gulisa Turashvili (U of T: University of Toronto)H-Index: 27
view all 6 authors...
Endometrial carcinoma is one of the prototypical malignancies associated with Lynch syndrome, an inherited cancer syndrome most commonly caused by germline mutations in DNA mismatch repair (MMR) genes, although rare alternative mechanisms also exist. In this report, we describe a patient first diagnosed with colorectal cancer at age 33, then vulvar squamous cell carcinoma, facial sebaceous adenoma/sebaceoma and finally endometrial carcinoma at age 52. All tumors were MLH1/PMS2-deficient by immun...
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#1Cécile Le PageH-Index: 23
#1Cécile Le Page (McGill University)H-Index: 2
Last. Kurosh RahimiH-Index: 16
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Uterine sarcomas represent a clinical challenge because of their difficult diagnosis and the poor prognosis of certain subtypes. The aim of this study was to evaluate the expression of the special AT-rich sequence-binding protein 2 (SATB2) in endometrial stromal sarcoma (ESS) and other types of uterine sarcoma by immunohistochemistry. We studied the expression of SATB2 on 71 full tissue sections of endometrial stromal nodule, low-grade ESS, uterine leiomyomas and leiomyosarcoma, undifferentiated...
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#1Nissreen Mohammad (UBC: University of British Columbia)H-Index: 2
#2Colin J.R. Stewart (UWA: University of Western Australia)H-Index: 30
Last. Cheng-Han LeeH-Index: 33
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#1Maria C. Cusimano (U of T: University of Toronto)H-Index: 4
#2Danielle Vicus (U of T: University of Toronto)H-Index: 10
Last. Sarah E. Ferguson (U of T: University of Toronto)H-Index: 24
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Importance Whether sentinel lymph node biopsy (SLNB) can replace lymphadenectomy for surgical staging in patients with high-grade endometrial cancer (EC) is unclear. Objective To examine the diagnostic accuracy of, performance characteristics of, and morbidity associated with SLNB using indocyanine green in patients with intermediate- and high-grade EC. Design, setting, and participants In this prospective, multicenter cohort study (Sentinel Lymph Node Biopsy vs Lymphadenectomy for Intermediate-...
11 CitationsSource
#1Jessie M. Wu (U of T: University of Toronto)H-Index: 1
#2Andrey-Ann Galibois (U of T: University of Toronto)
Last. Gulisa Turashvili (U of T: University of Toronto)H-Index: 27
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CONTEXT Fluorescence in situ hybridization (FISH) analysis is recommended for invasive breast carcinomas with equivocal (2+) immunohistochemical expression of human epidermal growth factor receptor 2 (HER2). However, existing guidelines for the retention and storage requirements for HER2 FISH slides vary widely among countries and laboratories. OBJECTIVE To determine the degradation rate of HER2 FISH signals, and the optimal retention time and storage conditions for HER2 FISH slides. DESIGN Dual...
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#1Anjelica HodgsonH-Index: 8
#1Anjelica Hodgson (Sunnybrook Health Sciences Centre)
Last. Gulisa TurashviliH-Index: 27
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The NTRK genes (NTRK1, NTRK2, and NTRK3) encode for TrkA, TrkB, and TrkC, neurotrophic tyrosine receptor kinases which serve a variety of functions including in the regulation of pathways involved in carcinogenesis. A number of reports have described NTRK gene fusions in a variety of adult and pediatric tumor types from various organ systems including the central nervous system, thyroid gland, breast, and soft tissue. NTRK-rearranged uterine sarcomas are a recently described group of tumors whic...
4 CitationsSource
#1Polycarp Erivwo (MUN: Memorial University of Newfoundland)
#2Gulisa Turashvili (U of T: University of Toronto)H-Index: 27
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#1Jessie M. Wu (U of T: University of Toronto)H-Index: 1
#2Gulisa Turashvili (U of T: University of Toronto)H-Index: 27
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#1Anne Grabenstetter (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 3
#2Conxi LázaroH-Index: 54
Last. Gulisa Turashvili (U of T: University of Toronto)H-Index: 27
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#1Gulisa Turashvili (U of T: University of Toronto)H-Index: 27
#2Conxi LázaroH-Index: 54
Last. Jordan Lerner-EllisH-Index: 13
view all 11 authors...
1 CitationsSource