Chao Fang
Huazhong University of Science and Technology
Publications 1
#1Yun Wang (SJTU: Shanghai Jiao Tong University)H-Index: 1
#2Jian-Hua Mao (SJTU: Shanghai Jiao Tong University)H-Index: 55
Last. Jin Wang (SJTU: Shanghai Jiao Tong University)H-Index: 28
view all 13 authors...
Platelet-targeted FVIII gene therapy can efficiently recover bleeding phenotype for hemophilia A (HA), yet characteristics of thrombus formation with this ectopic expression of factor VIII (FVIII) in platelets remain unclear. Here, we generated 2bF8trans mice restrictively expressing human B-domain–deleted FVIII (hBDD FVIII) in platelets on a hemophilic (FVIIInull) mice background. The results showed no statistical difference in clot strength and stability between wild-type (WT) and 2bF8trans mi...
This website uses cookies.
We use cookies to improve your online experience. By continuing to use our website we assume you agree to the placement of these cookies.
To learn more, you can find in our Privacy Policy.