Norma Velázquez-Guadarrama
Colloidal goldSiderophoreDrug resistanceHSP60CytoplasmBacterial cell structureInclusion bodiesHuman pathogenPneumococcal infectionsHelicobacter pyloriPneumoniaStreptococcus pneumoniaeBacteriaEscherichia coliBiochemistryMedicineChaperoninBiologyGroELMicrobiology
2Publications
2H-index
43Citations
Publications 2
Newest
#1Edgar Augusto Ortiz-Benítez (IPN: Instituto Politécnico Nacional)H-Index: 1
Last. José de Jesús Olivares-Trejo (UACM: Universidad Autónoma de la Ciudad de México)H-Index: 13
view all 5 authors...
Streptococcus pneumoniae is a causal agent of otitis media, pneumonia, meningitis and severe cases of septicemia. This human pathogen infects elderly people and children with a high mortality rate of approximately one million deaths per year worldwide. Antibiotic-resistance of S. pneumoniae strains is an increasingly serious health problem; therefore, new therapies capable of combating pneumococcal infections are indispensable. The application of gold nanoparticles has emerged as an option in th...
19 CitationsSource
#1Marco Antonio González-López (UACM: Universidad Autónoma de la Ciudad de México)H-Index: 4
Last. José de Jesús Olivares-Trejo (UACM: Universidad Autónoma de la Ciudad de México)H-Index: 13
view all 4 authors...
Helicobacter pylori is a bacterium that can use multiple iron sources. However, it is unknown whether this bacterium secretes molecules such as siderophores or haemophores to scavenge iron. Here, we report the first secreted iron-binding protein of H. pylori, which we purified by haem-affinity chromatography. Mass spectrometry analysis revealed its identity as chaperonin (HpGroEL). When we compared HpGroEL with EcGroEL from Escherichia coli, they were homologous, showing 60% similarity. Addition...
25 CitationsSource