Eleni Demetriou
UCL Institute of Neurology
Biomedical engineeringSaturation (chemistry)Magnetic resonance imagingHyperintensitySaturation (magnetic)ChemistryField strengthMaterials scienceIn vivoGrey matterScannerLesionWhite matterSignal SensitivityRelaxation rateGlucose infusionSaturation transferChemical exchangeSignificant differenceBody regionNuclear magnetic resonance
Publications 3
#1Mina Kim (UCL: University College London)H-Index: 3
#2Aaron Kujawa (UCL: University College London)H-Index: 3
Last. Xavier Golay (UCL: University College London)H-Index: 60
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PURPOSE: To translate the recently developed PRO-QUEST (Progressive saturation for quantifying exchange rates using saturation times) sequence from preclinical 9.4T to 3T clinical magnetic field strength. METHODS: Numerical simulations were performed to define the optimal saturation flip angles for PRO-QUEST saturation pulses at 3T and demonstrate the effect of a T2 error on the exchange rate (kex ) estimation at various field strengths. Exchange-dependent relaxation rate (Rex ) was measured for...
1 CitationsSource
#1Mina Kim (UCL: University College London)H-Index: 3
#2F Torrealdea (UCLH: University College Hospital)H-Index: 1
Last. Xavier GolayH-Index: 60
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Background: The aim of this study was to translate dynamic glucose enhancement (DGE) body magnetic resonance imaging (MRI) based on the glucose chemical exchange saturation transfer (glucoCEST) signal to a 3 T clinical field strength. Methods: An infusion protocol for intravenous (i.v.) glucose was optimised using a hyperglycaemic clamp to maximise the chances of detecting exchange-sensitive MRI signal. Numerical simulations were performed to define the optimum parameters for glucoCEST measureme...
8 CitationsSource
#1Mina KimH-Index: 3
Last. Xavier GolayH-Index: 60
view all 10 authors...