Shi-Yu Liu
Anhui Agricultural University
Surface plasmon resonanceQuenching (fluorescence)Serum albuminBioavailabilityStereoselectivityChemistryHuman serum albuminAffinitiesSpectroscopyStereochemistry
Publications 2
#1Shi-Yu Liu (AAU: Anhui Agricultural University)H-Index: 1
#2Wang Wei (AAU: Anhui Agricultural University)H-Index: 1
Last. Guan-Hu Bao (AAU: Anhui Agricultural University)H-Index: 21
view all 6 authors...
Abstract null null Background and purpose null Previous studies suggest that major Camellia sinensis (tea) catechins can inhibit 3-chymotrypsin-like cysteine protease (3CLpro), inspiring us to study 3CLpro inhibition of the recently discovered catechins from tea by our group. null null null Methods null Autodock was used to dock 3CLpro and 16 tea catechins. Further, a 3CLpro activity detection system was used to test their intra and extra cellular 3CLpro inhibitory activity. Surface plasmon reso...
#3Gang-Xiu Chu (AAU: Anhui Agricultural University)H-Index: 5
#4Guan-Hu Bao (AAU: Anhui Agricultural University)H-Index: 21
Abstract null null Formation of catechins-human serum albumin (HSA) complex contributes to stably transporting catechins and regulating their bioavailability. Recently, a new class of catechins namely flavoalkaloids have been reported from tea. The unique structural modification with an N-ethyl-2-pyrrolidinone ring at catechins from these flavoalkaloids has raised our interest in their HSA binding affinity. Thus, we investigated the interaction between HSA and flavoalkaloids by molecular docking...
This website uses cookies.
We use cookies to improve your online experience. By continuing to use our website we assume you agree to the placement of these cookies.
To learn more, you can find in our Privacy Policy.