Chenchen He
University of Michigan
AnalyteInternal medicineEndocrinologyRenal functionMass spectrometryChemistryPhosphatidylcholineDerivatizationType 2 diabetesFormic acidMetaboliteSample preparationPhospholipidPhosphatidylethanolamineType 1 diabetesBenzoyl chlorideChromatographyFatty acidDiabetes mellitusMedicineQuantitative analysis (chemistry)
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#1Jonathan B. Thacker (UM: University of Michigan)
#1Jonathan B Thacker (UM: University of Michigan)
Last. Subramaniam Pennathur (UM: University of Michigan)H-Index: 45
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γ-Glutamylpeptides have been identified as potential biomarkers for a number of diseases including cancer, diabetes, and liver disease. In this study, we developed and validated a novel quantitative analytical strategy for measuring γ-glutamylisoleucine, γ-glutamylthreonine, and γ-glutamylvaline, all of which have been previously reported as potential biomarkers for prostate cancer, in HeLa cells using UHPLC-MS/MS. A BEH C18 column was used as the stationary phase. Mobile phase A was 99:1 water:...
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