Donglin Chen
Sichuan University
Biological activityCytotoxic T cellChemistryIn vitroAlkaloidVeratramineFritillariaFritillaria thunbergiiCell growthStereochemistry
Publications 1
#1Cuilin He (Sichuan University)
#2Xinghong Liu (Sichuan University)
Last. Donglin Chen (Sichuan University)
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A new alkaloid named zhebeisine (1), together with four known compounds, eduardine (2), zhebeirine (3), isoverticine (4), and verticine (5), was isolated from the bulbs of Fritillaria thunbergii Miq. The structure of the new compound was elucidated on the basis of extensive spectroscopic methods and the in vitro biological activities of it were evaluated as well. Compound 1 features a veratramine skeleton with a rare 6/6/5/6/6/6 fused-ring system, representing the first reported veratramine-type...