Yuanbin Xie
Hainan Medical University
Gene expressionCell fate determinationRegulation of gene expressionNeuroscienceDNA methylationN6-MethyladenosineMRNA methylationRNABiologyCRISPR
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#1Godwin Sokpor (RUB: Ruhr University Bochum)H-Index: 1
#2Yuanbin Xie (HMU: Hainan Medical University)
Last. Tran Tuoc (RUB: Ruhr University Bochum)H-Index: 16
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Dynamic modification of RNA affords proximal regulation of gene expression triggered by non-genomic or environmental changes. One such epitranscriptomic alteration in RNA metabolism is the installation of a methyl group on adenosine (m6A) known to be the most prevalent modified state of mRNA in the mammalian cell. The methylation machinery responsible for the dynamic deposition and recognition of m6A on mRNA is composed of subunits that play specific roles, including reading, writing and erasing...
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