Peifang Cong
Northeastern University (China)
Self-healing hydrogelsMolecular biologyTerminal deoxynucleotidyl transferaseProinflammatory cytokineAndrologyChemistryApoptosisMaterials scienceTUNEL assayGranulation tissueOxidative stressInflammationHyaluronic acidNitric oxide synthaseMelatoninMalondialdehydeWound healingAngiogenesisLung injuryThioredoxinReactive oxygen speciesMedicineProtein kinase BPI3K/AKT/mTOR pathwayPharmacology
3Publications
1H-index
6Citations
Publications 4
Newest
#1Peifang Cong (Northeastern University (China))H-Index: 1
Last. Mingxiao Hou (Shenyang Medical College)
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Blast injuries include the various types of internal and external trauma caused by the impact force of high-speed blast waves with multiple mechanisms involved. Thoracic blast exposure could induce neurotrauma as well, but effective therapies are lacking. Resveratrol is a polyphenol flavonoid secreted by plants and has been shown to provide cardiovascular protection and play anti-inflammatory, anti-oxidation and anti-cancer roles. However, the effects of resveratrol on thoracic blast exposure-in...
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#1Kai Chen (Shangrao Normal University)H-Index: 1
#2Changci TongH-Index: 7
Last. Yunen LiuH-Index: 5
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Abstract Carboxymethyl chitosan (CMCS)-based hydrogels have antibacterial activity, and have shown the abilities of preventing wound infection, promoting cell proliferation, accelerating collagen deposition, and stimulating hyaluronic acid formation during wound healing. As a hormone produced by the pineal gland in humans and animals, melatonin promotes skin wound healing by regulating the release of inflammatory mediators and accelerating the proliferation and migration of cells, angiogenesis, ...
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#1Peifang Cong (Northeastern University (China))H-Index: 1
#2Changci TongH-Index: 7
Last. Mingxiao Hou (Northeastern University (China))H-Index: 1
view all 10 authors...
Blast exposure is a worldwide public health concern, but most related research has been focused on direct injury. Thoracic blast exposure-induced neurotrauma is a type of indirect injuries where research is lacking. As CD28 stimulates T cell activation and survival and contributes to inflammation initiation, it may play a role in thoracic blast exposure-induced neurotrauma. However, it has not been investigated. To explore the effects of CD28 on thoracic blast exposure-induced brain injury and i...
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#1Yunen LiuH-Index: 5
#2Changci TongH-Index: 7
Last. Mingxiao HouH-Index: 1
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Although CD28 is associated with the expression of inflammatory mediators, apoptosis-related protein, immunosuppression, and tumorigenesis, the effects of CD28 deficiency on blast exposure-induced lung injury have not been investigated. In this study, we have explored the effects of CD28 on blast exposure-induced lung injury and studied its potential molecular mechanisms. A mouse model of blast exposure-induced acute lung injury was established. Sixty C57BL/6 wild-type (WT) and CD28 knockout (CD...
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