Claudio Fiorino
Vita-Salute San Raffaele University
OpticsInternal medicineRadiologyUrologySurgeryOncologyMaterials scienceMedical physicsRadiation treatment planningProstateTomotherapyProstatectomyProstate cancerRectumPopulationToxicityNuclear medicineProportional hazards modelRadiation therapyMedicineDosimetry
Publications 290
#1Martin A. Ebert (SCGH: Sir Charles Gairdner Hospital)H-Index: 26
#2Sarah L. Gulliford (UCLH: University College London Hospitals NHS Foundation Trust)H-Index: 23
Last. Claudio Fiorino (UniSR: Vita-Salute San Raffaele University)H-Index: 55
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For decades, dose-volume information for segmented anatomy has provided the essential data for correlating radiotherapy dosimetry with treatment-induced complications. Dose-volume information has formed the basis for modelling those associations via normal tissue complication (NTCP) models and for driving treatment planning. Limitations to this approach have been identified. Many studies have emerged demonstrating that the incorporation of information describing the spatial nature of the dose di...
#1Tiziana RancatiH-Index: 27
#2Claudio Fiorino (UniSR: Vita-Salute San Raffaele University)H-Index: 55
Last. Ester OrlandiH-Index: 23
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#1Davide CusumanoH-Index: 10
#2Luca BoldriniH-Index: 16
Last. Luca IndovinaH-Index: 9
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Abstract Over the last years, technological innovation in Radiotherapy (RT) led to the introduction of Magnetic Resonance-guided RT (MRgRT) systems. Due to the higher soft tissue contrast compared to on-board CT-based systems, MRgRT is expected to significantly improve the treatment in many situations. MRgRT systems may extend the management of inter- and intra-fraction anatomical changes, offering the possibility of online adaptation of the dose distribution according to daily patient anatomy a...
#1M. MoriH-Index: 5
#2Diego PalumboH-Index: 5
Last. Claudio FiorinoH-Index: 55
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Abstract Purpose To train and validate a predictive model of mortality for hospitalized COVID-19 patients based on lung densitometry. Methods Two-hundred-fifty-one patients with respiratory symptoms underwent CT few days after hospitalization. “Aerated” (AV), “consolidated” (CV) and “intermediate” (IV) lung sub-volumes were quantified by an operator-independent method based on individual HU maximum gradient recognition. AV, CV, IV, CV/AV, IV/AV, and HU of the first peak position were extracted. ...
Abstract Purpose To implement knowledge-based (KB) automatic planning for helical TomoTherapy (HTT). The focus of the first clinical implementation was the case of high-risk prostate cancer, including pelvic node irradiation. Methods and Materials One hundred two HTT clinical plans were selected to train a KB model using the RapidPlan tool incorporated in the Eclipse system (v13.6, Varian Inc). The individually optimized KB-based templates were converted into HTT-like templates and sent automati...
#1Andrea BresolinH-Index: 1
#2Adriana FaiellaH-Index: 5
Last. Cesare CozzariniH-Index: 43
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Abstract Background and purpose To assess bowel dose-volume relationships for acute patient-reported intestinal symptoms of patients treated with whole-pelvis intensity-modulated radiotherapy (WPRT) for prostate cancer. Materials and methods Complete data of 415 patients enrolled in a multi institute, prospective trial (#NCT02803086) treated with radical (31%), adjuvant (33%) and salvage (36%) intent at a median dose to pelvic nodes/lymph-nodal area of 53Gy were available. The most severe change...
#1Giulia BenedettiH-Index: 13
#2M. MoriH-Index: 5
Last. Francesco De CobelliH-Index: 45
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PURPOSE To assess the ability of radiomic features (RF) extracted from contrast-enhanced CT images (ceCT) and non-contrast-enhanced (non-ceCT) in discriminating histopathologic characteristics of pancreatic neuroendocrine tumors (panNET). METHODS panNET contours were delineated on pre-surgical ceCT and non-ceCT. First- second- and higher-order RF (adjusted to eliminate redundancy) were extracted and correlated with histological panNET grade (G1 vs G2/G3), metastasis, lymph node invasion, microsc...
#1Andrei FodorH-Index: 13
#2Chiara Brombin (UniSR: Vita-Salute San Raffaele University)H-Index: 15
Last. N. Di Muzio (UniSR: Vita-Salute San Raffaele University)H-Index: 11
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Abstract Aim We report molecular subtype impact on 1325 early breast cancer (BCa) patients treated with whole breast hypofractionated (WBH) adjuvant forward-planned intensity modulated radiotherapy (F-IMRT) without boost. Methods and materials From 02/2009-05/2017 1325 patients with pTis-pT3, pNx-N1aM0 BCa who underwent breast conservation surgery were treated with WBHF-IMRT in our institute, to a total dose of 40 Gy/15 fractions, without boost. Median age: 62 (interquartile range-IQR-:51.14–70....
#1Aldo MazzilliH-Index: 1
#2C. FiorinoH-Index: 7
Last. Antonella del VecchioH-Index: 12
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#1Claudio FiorinoH-Index: 55
#1C. FiorinoH-Index: 7
Last. Nuria JornetH-Index: 16
view all 9 authors...