Xiaoyi Mao
University of Göttingen
CorticogenesisProtein–protein interactionFunction (biology)Cell signalingTranscriptomeChromatin remodelingChemistryProgenitor cellTranscriptional regulationPeptideProtein BiochemistryCell cycleEpigeneticsProteomicsMutationHigh-throughput screeningComputational biologyTranscription factorBiologyCell biology
Publications 2
#2Godwin Sokpor (RUB: Ruhr University Bochum)H-Index: 1
Last. Tran Tuoc (RUB: Ruhr University Bochum)H-Index: 16
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Summary Identification of peptides mediating protein-protein interaction (PPI) is crucial for understanding the function of interlinked proteins in cellular processes and amino acid-associated diseases. Traditional PPI assays are laborious, involving the generation of many truncated proteins. SPOT peptide assay allows high-throughput detection of domains essential for PPI by synthesizing several hundred peptides on a cellulose membrane. Here, we present a rapid SPOT peptide protocol for identify...
#1Pauline Antonie Ulmke (GAU: University of Göttingen)H-Index: 2
#2M. Sadman Sakib (German Center for Neurodegenerative Diseases)H-Index: 6
Last. Tran Tuoc (GAU: University of Göttingen)H-Index: 16
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Summary Intermediate progenitor cells (IPCs) are neocortical neuronal precursors. Although IPCs play crucial roles in corticogenesis, their molecular features remain largely unknown. In this study, we aimed to characterize the molecular profile of IPCs. We isolated TBR2-positive (+) IPCs and TBR2-negative (−) cell populations in the developing mouse cortex. Comparative genome-wide gene expression analysis of TBR2+ IPCs versus TBR2− cells revealed differences in key factors involved in chromatid ...