Alexandria Sarah Kidd
Hull York Medical School
PathologySkin repairEx vivoBiopsyHuman skinWound healingFixativeChronic woundMedicineStaining
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Chronic non-healing wounds, which primarily affect the elderly and diabetic, are a significant area of clinical unmet need. Unfortunately, current chronic wound treatments are inadequate, while available pre-clinical models poorly predict the clinical efficacy of new therapies. Here we describe a high throughput, pre-clinical model to assess multiple aspects of the human skin repair response. Partial thickness wounds were created in human ex vivo skin and cultured across a healing time course. S...
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