Yolanda Aladro-Benito
CancerInternal medicineNeuropsychologyMagnetic resonance imagingCognitionProspective cohort studyMedical recordLeiomyosarcomaMalignancyMultiple sclerosisPopulationCognitive impairmentRisk factorBreast cancerCognitive testMedicineCohortGastroenterology
Publications 2
Abstract Background Potential increase of cancer incidence is one of the main safety concerns of the disease-modifying therapies employed in Multiple Sclerosis (MS). Objective : Detailed description of patients who developed cancer among a prospective cohort of Spanish MS patients on dimethyl fumarate (DMF) treatment. Methods We describe patients who developed cancer among a cohort of 886 MS patients on DMF treatment (2681 patient-years), with a median time of exposure of 39.5 months (IQR 23-51....
#1Ángela Domingo-Santos (Foundation for Biomedical Research)
Last. Julián Benito-León (Complutense University of Madrid)H-Index: 61
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Abstract Up to a third of patients with radiologically isolated syndrome (RIS) exhibit lower-than-expected cognitive performances in neuropsychological evaluations, but the relationship between cognitive impairment (CI) and quantitative magnetic resonance (MRI) measures has not been stablished. Furthermore, the prognostic role of CI in RIS for conversion to MS is currently unknown. We assessed 17 patients with RIS and 17 matched healthy controls (HC) with a neurophychological battery and a 3T MR...