Megan Schmidt
Internal medicineSurgeryOdds ratioRandomized controlled trialAdverse effectObservational studyPlaceboOcclusionARDSIntensive care unitCorticosteroidMechanical ventilationIntracerebral hemorrhageLopinavirDiseaseRitonavirCerebral infarctionThrombolysisModified Rankin ScaleLopinavir/ritonavirPopulationAcute respiratory distressArtificial respiration2019-20 coronavirus outbreakSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)Convalescent plasmaLength of hospitalizationWeb of scienceConfidence intervalPharmacotherapyMedicineMeta-analysis
Publications 5
#1John M. PedersonH-Index: 2
Last. Kevin M. Kallmes (Duke University)H-Index: 5
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BACKGROUND Balloon guide catheters (BGCs) are designed to induce flow arrest during mechanical thrombectomy procedures for acute ischemic stroke due to large-vessel occlusion and have been associated with improved clinical and angiographic outcomes. We conducted a systematic review and meta-analysis evaluating the relative technical and clinical outcomes associated with BGC versus non-BGC approaches. METHODS A systematic review of clinical literature using the PubMed database was undertaken to i...
Objectives: To systematically review the clinical literature reporting the use of Lopinavir/ritonavir (LPV/r) for the treatment of patients with COVID-19 to assess the efficacy of LPV/r for the treatment of Cornonavirus disease 19 (COVID-19). Methods: The authors systematically searched PubMed and MedRxiv databases for studies describing treatment of COVID-19 patients using LPV/r compared to other therapies. Articles were excluded if they were case reports, opinion editorials, preclinical studie...
1 CitationsSource
#1Yashwitha Sai Pulakurthi (Academy of Medical Sciences, United Kingdom)H-Index: 2
#2John M. PedersonH-Index: 2
Last. Kirk W. EvansonH-Index: 1
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BACKGROUND Corticosteroid treatment is an effective and common therapeutic strategy for various inflammatory lung pathologies and may be an effective treatment for coronavirus disease 2019 (COVID-19). The purpose of this systematic review and meta-analysis of current literature was to investigate the clinical outcomes associated with corticosteroid treatment of COVID-19. METHODS We systematically searched PubMed, medRxiv, Web of Science, and Scopus databases through March 10, 2021 to identify ra...
1 CitationsSource
#1Adam A. Dmytriw (Brigham and Women's Hospital)H-Index: 14
#2Richa Chibbar (Lakeridge Health)H-Index: 1
Last. Praneeth Reddy Keesari (Academy of Medical Sciences, United Kingdom)H-Index: 1
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INTRODUCTION Acute respiratory distress syndrome (ARDS) due to coronavirus disease 2019 (COVID-19) often leads to mortality. Outcomes of patients with COVID-19-related ARDS compared to ARDS unrelated to COVID-19 have not been well characterized. AREAS COVERED We performed a systematic review of PubMed, Scopus, and MedRxiv 11/1/2019 to 3/1/2021, including studies comparing outcomes in patients with COVID-19-related ARDS (COVID-19 group) and ARDS unrelated to COVID-19 (ARDS group). Outcomes invest...
#1Charan Thej Reddy Vegivinti (Manipal University)H-Index: 1
#2John M. PedersonH-Index: 2
Last. Ameer E. HassanH-Index: 1
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The purpose of this systematic review and meta-analysis was to examine clinical outcomes associated with convalescent plasma therapy in COVID-19 patients. We performed a literature search on PubMed, medRxiv, Web of Science, and Scopus to identify studies published up to December 10th, 2020 that examined the efficacy of convalescent plasma treatment for COVID-19. The primary endpoints were mortality, clinical improvement, and hospital length of stay. We screened 859 studies that met the search cr...
3 CitationsSource