Vittorio Vavassori
Internal medicineRadiologyUrologySurgeryOncologyOdds ratioRetrospective cohort studyProspective cohort studyProstateChemotherapyFecal incontinenceHormonal therapyAbdominal surgeryProstate cancerRectumPopulationToxicityNuclear medicineRadiation therapyMedicineGastroenterology
Publications 65
#1Luca TriggianiH-Index: 15
#2Rosario MazzolaH-Index: 19
Last. Stefano Maria MagriniH-Index: 25
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The aim of the present study was to explore the potential impact of upfront metastases-directed therapy (MDT) in terms of prolongation of castration-sensitive phase in a series of oligorecurrent castration-sensitive prostate cancer (PC) patients. The present article is a multicenter retrospective study. The population of interest was castrate-sensitive oligorecurrent PC, defined as the presence of 1-3 uptakes in non-visceral sites such as bones or nodes detected by means of 18F-Choline PET/CT or...
#2Paolo GhirardelliH-Index: 6
Last. Vittorio VavassoriH-Index: 18
view all 5 authors...
#1Barbara Alicja Jereczek-Fossa (IEO: European Institute of Oncology)H-Index: 37
#2Mauro PalazziH-Index: 11
Last. Carlo Pietro SoattiH-Index: 4
view all 39 authors...
Lombardy has represented the Italian and European epicenter of the coronavirus disease 2019 (COVID-19) pandemic. Although most clinical efforts within hospitals were diverted towards the care of virally infected patients, therapies for patients with cancer, including radiotherapy (RT), have continued. During both the first and second pandemic waves, several national and regional organizations provided Italian and Lombardian RT departments with detailed guidelines aimed at ensuring safe treatment...
#1Andrea BresolinH-Index: 1
#2Adriana FaiellaH-Index: 5
Last. Cesare CozzariniH-Index: 43
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Abstract Background and purpose To assess bowel dose-volume relationships for acute patient-reported intestinal symptoms of patients treated with whole-pelvis intensity-modulated radiotherapy (WPRT) for prostate cancer. Materials and methods Complete data of 415 patients enrolled in a multi institute, prospective trial (#NCT02803086) treated with radical (31%), adjuvant (33%) and salvage (36%) intent at a median dose to pelvic nodes/lymph-nodal area of 53Gy were available. The most severe change...
#1Paolo GhirardelliH-Index: 6
#1Paolo GhirardelliH-Index: 1
Last. Giovanni L. Ceresoli (IEO: European Institute of Oncology)
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Abstract Objectives No standard treatment option is available for patients with unresectable malignant pleural mesothelioma (MPM) progressing after upfront chemotherapy. We aimed to explore the role of focal radiotherapy (FRT) as a treatment modality for oligo-progressive MPM. Materials and Methods In this retrospective study, consecutive patients pretreated with ≥1 lines of chemotherapy were included. Oligo-progressive MPM was defined as an unresectable disease with radiological progression at ...
1 CitationsSource
#1Barbara Alicja Jereczek-Fossa (IEO: European Institute of Oncology)H-Index: 37
#4Johannes Lars Isaksson (IEO: European Institute of Oncology)H-Index: 1
Last. Mauro PalazziH-Index: 1
view all 37 authors...
Italy experienced one of the world’s severest COVID-19 outbreak, with Lombardy being the most afflicted region. However, the imposed safety measures allowed to flatten the epidemic curve and hence to ease the restrictions and inaugurate, on the 4th of May 2020, the Italian phase (P) 2 of the pandemic. The present survey study, endorsed by CODRAL and AIRO-L, aimed to assess how radiotherapy (RT) departments in Lombardy have dealt with the recovery. A questionnaire dealing with the management of p...
2 CitationsSource
#1Andrea Bresolin (UniSR: Vita-Salute San Raffaele University)H-Index: 1
Last. Cesare Cozzarini (UniSR: Vita-Salute San Raffaele University)
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Objective. To investigate predictors of patient-reported urinary incontinence (PRUI) in the first 2 years after post-prostatectomy radiotherapy (PORT) with particular emphasis on possible dose-effect relationships. Patients and Methods. Two-hundred-thirteen patients, whose clinical and dosimetric data were prospectively collected within a registered multi-institutional cohort study, underwent PORT with adjuvant (n=106) or salvage (n=107) intent with conventional (n=123, prescribed dose to the pr...
#1Marta Scorsetti (Humanitas University)H-Index: 44
#2Davide FranceschiniH-Index: 19
Last. Vittorio VavassoriH-Index: 18
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The role of radiotherapy in the management of malignant pleural mesothelioma is still matter of debate. Traditionally, radiotherapy has been used in four possible scenarios: as prophylactic treatment to prevent procedure tract metastases; as palliative treatment for the management of painful lesions; as adjuvant treatment after surgical interventions; and as definitive treatment in inoperable patients with locoregional disease, usually after chemotherapy.
#1Mauro CarraraH-Index: 16
#2Eleonora MassariH-Index: 2
Last. Riccardo Valdagni (University of Milan)H-Index: 50
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Purpose This study was designed to apply artificial neural network (ANN) classification methods for the prediction of late fecal incontinence (LFI) after high-dose prostate cancer radiation therapy and to develop a ready-to-use graphical tool. Materials and Methods In this study, 598 men recruited in 2 national multicenter trials were analyzed. Information was recorded on comorbidity, previous abdominal surgery, use of drugs, and dose distribution. Fecal incontinence was prospectively evaluated ...
4 CitationsSource
#1Alessandro Cicchetti (UNIPV: University of Pavia)H-Index: 7
#2Barbara AvuzziH-Index: 10
Last. Riccardo Valdagni (University of Milan)H-Index: 50
view all 13 authors...
Purpose This study aimed to validate a previously published predictive model for late fecal incontinence (FI) in a contemporary population of prostate cancer patients treated with radical radiation therapy. Methods and Materials The validation included patients treated with intensity-modulated radiation therapy (IMRT) (2010-2014). Prescribed dose range was 65-80 Gy, including conventional and moderate hypo-fractionated treatments. Rectal toxicity was scored using LENT/SOMA, a minimum 2-year foll...
7 CitationsSource