Javier Mancilla-Galindo
National Autonomous University of Mexico
EpidemiologySupine positionInternal medicineProne positionSocial inequalityRetrospective cohort studyPropensity score matchingPediatricsCohort studyImmunologyMedical historyARDSHypoxemiaCoronavirusKidney diseaseIntubationLower riskOxygen therapyPopulationEpidemiologic SurveillanceSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)In patientMexico cityAnesthesiaInequalityProportional hazards modelRisk factorMedicinePandemicEnvironmental health
12Publications
3H-index
18Citations
Publications 11
Newest
Last. Luis Alberto Macias-Garcia (Institute for Social Security and Services for State Workers)
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The awake prone position (AP) strategy for patients with acute respiratory distress syndrome (ARDS) is a safe, simple, and cost-effective technique used to improve hypoxemia. We aimed to evaluate intubation and mortality risk in patients with coronavirus disease (COVID-19) who underwent AP during hospitalisation.In this retrospective, multicentre observational study conducted between May 1 and June 12, 2020 in 27 hospitals in Mexico and Ecuador, non-intubated patients with COVID-19 managed with ...
1 CitationsSource
#2Javier Mancilla-Galindo (UNAM: National Autonomous University of Mexico)H-Index: 3
Last. J de J Vidal-MayoH-Index: 1
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Conflicting results have been obtained through meta-analyses for the role of obesity as a risk factor for adverse outcomes in patients with coronavirus disease-2019 (COVID-19), possibly due to the inclusion of predominantly multimorbid patients with severe COVID-19. Here, we aimed to study obesity alone or in combination with other comorbidities as a risk factor for short-term all-cause mortality and other adverse outcomes in Mexican patients evaluated for suspected COVID-19 in ambulatory units ...
3 CitationsSource
The impact of the COVID-19 pandemic in Mexico City has been sharp, as several social inequalities coexist with chronic comorbidities. Here, we conducted an in-depth evaluation of the impact of social, municipal, and individual factors on the COVID-19 pandemic in working-age population living in Mexico City. To this end, we used data from the National Epidemiological Surveillance System; furthermore, we used a multidimensional metric, the social lag index (DISLI), to evaluate its interaction with...
6 CitationsSource
#1Javier Mancilla-Galindo (UNAM: National Autonomous University of Mexico)H-Index: 3
#2Jorge García-Méndez (UNAM: National Autonomous University of Mexico)H-Index: 2
Last. Ashuin Kammar-GarcíaH-Index: 4
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The aim of our study was to evaluate all-cause mortality risk in patients with laboratory-confirmed COVID-19 in Mexico City treated with repurposed antivirals and antibiotics. This real-world retrospective cohort study contemplated 395,343 patients evaluated for suspected COVID-19 between February 24 and September 14, 2020 in 688 primary-to-tertiary medical units in Mexico City. Patients were included with a positive RT-PCR for SARS-CoV-2; those receiving unspecified antivirals, excluded; and gr...
2 CitationsSource
#2Diego Escarramán-Martínez (Mexican Social Security Institute)
Last. Silvio A. Ñamendys-SilvaH-Index: 15
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Purpose: The awake prone position (PP) strategy for patients with acute respiratory distress syndrome (ARDS) is a safe, simple, and cost-effective technique used to improve hypoxemia. We aimed to evaluate the relationship between awake PP (AP) and endotracheal intubation in patients with coronavirus disease (COVID-19). Methods: In this retrospective, multicentre observational study conducted between 1 May and 12 June 2020 in 27 hospitals in Mexico and Ecuador, non-intubated patients with COVID-1...
1 CitationsSource
#1Addí Rhode Navarro-Cruz (BUAP: Benemérita Universidad Autónoma de Puebla)H-Index: 7
Last. Orietta Segura-BadillaH-Index: 4
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In this cross-sectional analytical study, we evaluated the effect of changes in dietary behaviours and lifestyle on weight gain during the COVID-19 lockdown in Chile. Five surveys were condensed into an 86-item online questionnaire comprising general and sociodemographic history, eating habits and lifestyle before and during confinement, emotional influence on eating behaviour, and food safety. Of 639 respondents, mean weight gain was 1.99 kg and 0.7 units of BMI. Increased dietary intake of mos...
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We conducted a retrospective observational study in patients with laboratory-confirmed COVID-19 who received medical care in 688 COVID-19. Patients were categorized into 8 groups (<20, 20-29, 30-39, 40-49, 50-59, 60-69, 70-79, and 80 years). Symptoms at initial presentation were classified according to a previously validated classification into respiratory and non-respiratory symptoms. Comparisons between time from symptom onset to medical care for every age category were done through ANOVA. Lo...
2 CitationsSource
#1María Magdalena Aguirre García (UNAM: National Autonomous University of Mexico)H-Index: 1
#2Javier Mancilla-Galindo (UNAM: National Autonomous University of Mexico)H-Index: 3
Last. Nydia Ávila-VanzziniH-Index: 1
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The pandemic SARS coronavirus 2 utilizes efficient mechanisms to establish infection and evade the immune system Established infection leads to severe inflammation in susceptible patients, the main hallmark of progression to severe coronavirus disease (COVID-19) Knowledge of the mechanisms of disease has expanded rapidly As inflammation emerges as the central pathophysiological feature in COVID-19, elucidating how the immune system, lungs and gut communicate and interact with microbial component...
2 CitationsSource
#1Javier Mancilla-Galindo (UNAM: National Autonomous University of Mexico)H-Index: 3
Increased transmissibility of the pandemic severe acute respiratory coronavirus 2 (SARS-CoV-2) has been noted to occur at lower ambient temperatures. This is seemingly related to a better replication of most respiratory viruses, including SARS-CoV-2, at lower-than-core body temperatures (i.e., 33 °C vs 37 °C). Also, intrinsic characteristics of SARS-CoV-2 make it a heat-susceptible pathogen. Thermotherapy has successfully been used to combat viral infections in plants which could otherwise resul...
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#1Javier Mancilla-Galindo (UNAM: National Autonomous University of Mexico)H-Index: 3
Last. Ashuin Kammar-García (IPN: Instituto Politécnico Nacional)H-Index: 4
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Most of the existing prediction models for COVID-19 lack validation, are inadequately reported or are at high risk of bias, a reason which has led to discourage their use. Few existing models have the potential to be extensively used by healthcare providers in low-resource settings since many require laboratory and imaging predictors. Therefore, we sought to develop and validate a multivariable prediction model of death in Mexican patients with COVID-19, by using demographic and patient history ...
14 CitationsSource