Yasuhiro Nakano
Okayama University
Messenger RNAPhosphorylationInternal medicineDownregulation and upregulationEndocrinologySurgeryPathologyCardiologyReceptorCLOCKChemistryAldosteroneForskolinMEDLINEGlucocorticoidBone morphogenetic proteinText miningMedicineCholesterol side-chain cleavage enzymeBiologyCell biology
33Publications
3H-index
26Citations
Publications 32
Newest
#1Atsuhito Suyama (Okayama University)H-Index: 1
#2Nahoko Iwata (Okayama University)H-Index: 5
Last. Fumio Otsuka (Okayama University)H-Index: 35
view all 7 authors...
The functional role of the transcription factors NR5A1 and NR5A2 and their interaction with Clock gene and bone morphogenetic proteins (BMPs) were investigated in human granulosa KGN cells. Treatment with BMP-15 and GDF-9 suppressed forskolin (FSK)-induced steroidogenesis as shown by the mRNA expression levels of StAR and P450scc but not the mRNA expression level of P450arom. Of interest, treatment with BMP-15 and GDF-9 also suppressed FSK-induced NR5A2 mRNA expression. Treatment with BMP-15 sup...
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#1Ryosuke Takase (Okayama University)
#2Yasuhiro Nakano (Okayama University)H-Index: 3
Last. Fumio Otsuka (Okayama University)H-Index: 35
view all 4 authors...
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#1Yuki Otsuka (Okayama University)H-Index: 1
#2Hideharu Hagiya (Okayama University)H-Index: 5
Last. Fumio Otsuka (Okayama University)H-Index: 35
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The gold standard for the diagnosis of coronavirus disease 2019 (COVID-19) is a nucleic acid detection test for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which may occasionally reveal false-positive or false-negative results. Herein, we describe a case of a patient infected with human coronavirus NL63 (HCoV-NL63) who was falsely diagnosed with COVID-19 using the Ampdirect™ 2019-nCoV detection kit (Shimadzu Corporation, Japan) and SARS-CoV-2 Detection Kit (TOYOBO co., ltd.), a...
1 CitationsSource
#1Atsuhito Suyama (Okayama University)H-Index: 1
#2Nahoko Iwata (Okayama University)H-Index: 5
Last. Fumio Otsuka (Okayama University)H-Index: 35
view all 7 authors...
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#1Yuki Otsuka (Okayama University)H-Index: 1
#2Yasuhiro Nakano (Okayama University)H-Index: 3
Last. Fumio Otsuka (Okayama University)H-Index: 35
view all 8 authors...
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#1Koichiro Yamamoto (Okayama University)H-Index: 2
#2Manami Fujita (Okayama University)
Last. Fumio Otsuka (Okayama University)H-Index: 35
view all 9 authors...
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#1Yuki Otsuka (Okayama University)H-Index: 1
#2Yasuhiro Nakano (Okayama University)H-Index: 3
Last. Fumio Otsuka (Okayama University)H-Index: 35
view all 9 authors...
Objective null Urinary free cortisol (UFC) is a reliable marker to avoid cortisol fluctuation and the effects of binding proteins. However, UFC levels are affected by fluid intake and urine volume, and the normal levels range widely. null Methods null To discover the utility of the ratio of urinary cortisol to aldosterone excretions, 246 patients in whom daily excretions of UFC and aldosterone (UAC) were measured were retrospectively analyzed. null Results null The UFC/UAC ratio showed significa...
#1Chiaki Kashino (Okayama University)H-Index: 1
#2Toru Hasegawa (Okayama University)H-Index: 4
Last. Fumio Otsuka (Okayama University)H-Index: 35
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To elucidate the impact of glucocorticoids on ovarian steroidogenesis and its molecular mechanism by focusing on bone morphogenetic proteins (BMPs), we examined the effect of dexamethasone (Dex) on estradiol and progesterone synthesis by using primary culture of rat granulosa cells. It was revealed that Dex treatment dose-dependently decreased estradiol production but increased progesterone production induced by follicle-stimulating hormone (FSH) by granulosa cells. In accordance with the effect...
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#1Yuki Otsuka (Okayama University)H-Index: 1
#2Hideharu Hagiya (Okayama University)H-Index: 13
Last. Fumio Otsuka (Okayama University)H-Index: 35
view all 6 authors...
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#1Manami Fujita (Okayama University)
#2Yasuhiro Nakano (Okayama University)H-Index: 3
Last. Fumio Otsuka (Okayama University)H-Index: 35
view all 4 authors...
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