Asma Sardar
Hazara University
Proton NMRNanomaterialsNuclear chemistryNanoparticleCatalysisCarbon-13 NMRMolecular modelEnzymeChemistryMaterials scienceCombinatorial chemistrySolvothermal synthesisBromideIminePiperonalUreaseOxideThioureaAntimicrobialPulmonary surfactant
2Publications
1H-index
0Citations
Publications 2
Newest
#1Basit Ali ShahH-Index: 1
#2Bin YuanH-Index: 14
Last. Yu Yan
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#1Obaid-ur-Rahman Abid (HU: Hazara University)H-Index: 8
#2Saima Daud (HU: Hazara University)H-Index: 1
Last. Muhammad Yasir (HU: Hazara University)H-Index: 32
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A series of piperonal-based imines (3a–c) and bis-imines (5a-o) have been synthesized in search of new urease inhibitors. Synthesized compounds were characterized by 1H NMR, 13C NMR and EI-MS. These derivatives were subjected to evaluation of urease inhibitory potential, which exhibited a varied degree of potential, ranging from 41.7 ± 5.8 to 353.6 ± 5.8 µM, when compared with the standard inhibitor (i.e., thiourea having IC50 value 21.8 ± 1.51 µM). Amongst the synthesized bis-imines, three comp...
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