Martin Loos
University Hospital Heidelberg
Internal medicineRadiologySurgeryResectionMortality rateLymphatic systemAcute pancreatitisChemotherapyArteryAbdominal surgeryPancreatic cancerPancreatic fistulaHyperamylasemiaSerum amylaseDistal pancreatectomyIn patientPerioperativeMedicineCohortComplicationGastroenterology
10Publications
3H-index
13Citations
Publications 17
Newest
#1Martin Loos (University Hospital Heidelberg)H-Index: 3
#2Mohammed Al-Saeedi (University Hospital Heidelberg)H-Index: 10
Last. Markus W. Büchler (University Hospital Heidelberg)H-Index: 177
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Importance Comparability of morbidity and mortality rates after total pancreatectomy (TP) reported by different surgical centers is limited. Procedure-specific differences, such as the extent of resection, including additional vascular or multivisceral resections, are rarely acknowledged when postoperative outcomes are reported. Objectives To evaluate postoperative outcomes after TP and categorize different types of TP based on the extent, complexity, and technical aspects of each procedure. Des...
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#1Mohammed Al-Saeedi (University Hospital Heidelberg)H-Index: 10
#2Leonie Frank-Moldzio (University Hospital Heidelberg)
Last. Arianeb Mehrabi (University Hospital Heidelberg)H-Index: 40
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Resection of the portal venous confluence is frequently necessary for radical resection during pancreatoduodenectomy for cancer. However, ligation of the splenic vein can cause serious postoperative complications such as gastric/splenic venous congestion and left-sided portal hypertension. A splenorenal shunt (SRS) can maintain gastric and splenic venous drainage and mitigate these complications. This study describes the surgical technique, postoperative course, and surgical outcomes of SRS afte...
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#1Rosa Klotz (University Hospital Heidelberg)H-Index: 3
#2Charlotte Kuner (University Hospital Heidelberg)
Last. Martin Loos (University Hospital Heidelberg)H-Index: 3
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Abstract null null Background null Chyle leak is a common complication following pancreatic surgery. After failure of conservative treatment, lymphography is one of the last therapeutic options. The objective of this study was to evaluate whether lymphography represents an effective treatment for severe chyle leak (International study Group on Pancreatic Surgery, grade C) after pancreatic surgery. null null null Methods null Patients with grade C chyle leak after pancreatic surgery who received ...
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#1G. Peduzzi (UniPi: University of Pisa)H-Index: 1
#2Manuel Gentiluomo (UniPi: University of Pisa)H-Index: 6
Last. Luca Morelli (UniPi: University of Pisa)H-Index: 22
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Background The mitochondrial metabolism has been associated with pancreatic ductal adenocarcinoma (PDAC) risk. Recent evidence also suggests the involvement of the genetic variability of the mitochondrial function in several traits involved in PDAC aetiology. However, a systematic investigation of the genetic variability of mitochondrial genome (mtSNPs) and of all the nuclear genes involved in its functioning (n-mtSNPs) has never been reported. Methods We conducted a two-phase association study ...
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#1Ali Ramouz (University Hospital Heidelberg)H-Index: 6
#2Arianeb Mehrabi (University Hospital Heidelberg)H-Index: 40
Last. Martin Loos (University Hospital Heidelberg)H-Index: 3
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Abstract Postoperative (or postpancreatectomy) acute pancreatitis (PPAP) in the pancreatic remnant has recently been recognized as a distinct complication entity that may occur after both partial pancreatoduodenectomy (PD) and distal pancreatectomy (DP). However, it remains unclear what constitutes PPAP. Moreover, the pathophysiologic events leading to PPAP are not fully understood and no internationally accepted definition of PPAP exists. Recent studies mostly used an early postoperative increa...
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#1Martin Loos (University Hospital Heidelberg)H-Index: 3
#2Arianeb MehrabiH-Index: 40
Last. Markus W. BüchlerH-Index: 177
view all 18 authors...
OBJECTIVE The aim of this study was to determine the role of gastric venous congestion (GVC) in mortality after total pancreatectomy (TP). BACKGROUND Data from a nationwide administrative database revealed that TP is associated with a 23% mortality rate in Germany. METHODS A total of 585 consecutive patients who had undergone TP (n = 514) or elective completion pancreatectomy (n = 71) between January 2015 and December 2019 were analyzed. Univariable and multivariable analyses were performed to i...
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#1Philipp Mayer (University Hospital Heidelberg)H-Index: 9
#2Athanasios Giannakis (University Hospital Heidelberg)H-Index: 2
Last. Martin Loos (University Hospital Heidelberg)H-Index: 3
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Abstract Purpose This study aimed to evaluate contrast-enhanced computed tomography (CE-CT) features for prediction of arterial tumor invasion in pancreatic cancer (PDAC) patients in the event of arterial encasement >180° after neoadjuvant (radio-)chemotherapy (NAT). Methods Seventy PDAC patients with seventy-five arteries showing encasement >180° after completion of NAT were analyzed. All patients underwent surgical exploration with either tumor resection including arterial resection, periadven...
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#1Martin Loos (University Hospital Heidelberg)H-Index: 3
#2Thilo HackertH-Index: 57
Last. Markus W. BüchlerH-Index: 177
view all 3 authors...
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#1Martin Loos (University Hospital Heidelberg)H-Index: 3
#2Oliver Strobel (University Hospital Heidelberg)H-Index: 53
Last. Thilo Hackert (University Hospital Heidelberg)H-Index: 57
view all 18 authors...
Abstract Background Serum amylase activity greater than the institutional upper limit of normal (hyperamylasemia) on postoperative day 0-2 has been suggested as a criterion to define postoperative acute pancreatitis after pancreatoduodenectomy, but robust evidence supporting this definition is lacking. Background To assess the clinical impact of hyperamylasemia after pancreatoduodenectomy and to define postoperative acute pancreatitis. Methods Data of 1,235 consecutive patients who had undergone...
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#1M. von der ForstH-Index: 2
#2Sebastian WeitererH-Index: 8
Last. Benedikt Hermann SieglerH-Index: 6
view all 7 authors...
Die Gabe intravasaler Flussigkeiten gehort zu den Grundpfeilern der perioperativen Therapie und nimmt insbesondere bei grosen viszeralchirurgischen Eingriffen masgeblichen Einfluss auf das chirurgische Behandlungsergebnis. Ein adaquates perioperatives Flussigkeitsmanagement kann durch Vermeidung von Hypo- und Hypervolamie dazu beitragen, das Risiko einer unzureichenden Gewebeperfusion als Treiber postoperativer Morbiditat und Letalitat signifikant zu reduzieren. Der effektive Umgang mit intravas...
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