Jamshed Bomanji
University College London Hospitals NHS Foundation Trust
Correction for attenuationInternal medicineRadiologyPET-CTSurgeryPathologyOncologyAttenuationMedical physicsPositron emission tomographyOsteosarcomaProstate cancerNuclear medicineRadionuclide therapyIn patientFdg pet ctRadiation therapyColorectal cancerClinical trialMedicine
101Publications
12H-index
557Citations
Publications 102
Newest
#1Mechteld C de Jong (UCLH: University College London Hospitals NHS Foundation Trust)H-Index: 1
#1Mechteld C de Jong (UCLH: University College London Hospitals NHS Foundation Trust)H-Index: 1
Last. Tom R Kurzawinski (UCLH: University College London Hospitals NHS Foundation Trust)H-Index: 3
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AIM Differentiated thyroid cancer (DTC) in children and adolescents is rare and data about its presentation and management are not well known. The aim of this study was to provide evidence of the current practice in the United Kingdom before the launch of the Rare National Paediatric Endocrine Tumours Guidelines (to be published in 2020). METHODS Seventy-two children and adolescents with DTC (<18 years) who were treated at our institution between 2003 and 2018 were identified and their presentat...
2 CitationsSource
#1Francesco Ceci (UNITO: University of Turin)H-Index: 23
#1Francesco Ceci (UNITO: University of Turin)H-Index: 4
Last. Ken Herrmann (University of Duisburg-Essen)H-Index: 69
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Rationale The development of consensus guidelines for interpretation of Prostate-Specific Membrane Antigen (PSMA)-Positron Emission Tomography (PET) is needed to provide more consistent reports in clinical practice. The standardization of PSMA-PET interpretation may also contribute to increasing the data reproducibility within clinical trials. Finally, guidelines in PSMA-PET interpretation are needed to communicate the exact location of findings to referring physicians, to support clinician ther...
7 CitationsSource
#1Matthew D. Aldridge (UCLH: University College London Hospitals NHS Foundation Trust)H-Index: 5
#2Connie Peet (UCLH: University College London Hospitals NHS Foundation Trust)H-Index: 1
Last. Mark N. Gaze (UCLH: University College London Hospitals NHS Foundation Trust)H-Index: 28
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The common contemporary indications for paediatric molecular radiotherapy (pMRT) are differentiated thyroid cancer and neuroblastoma. It may also have value in neuroendocrine cancers, and it is being investigated in clinical trials for other diseases. pMRT is the prototypical biomarker-driven, precision therapy, with a unique mode of delivery and mechanism of action. It is safe and well tolerated, compared with other treatments. However, its full potential has not yet been achieved, and its wide...
1 CitationsSource
#1Ananth Shankar (UCLH: University College London Hospitals NHS Foundation Trust)H-Index: 14
#2Jamshed Bomanji (UCLH: University College London Hospitals NHS Foundation Trust)H-Index: 12
Last. Harpreet Hyare (UCLH: University College London Hospitals NHS Foundation Trust)H-Index: 5
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(1) Background: Standard magnetic resonance imaging (MRI) remains the gold standard for brain tumour imaging in paediatric and teenage and young adult (TYA) patients. Combining positron emission tomography (PET) with MRI offers an opportunity to improve diagnostic accuracy. (2) Method: Our single-centre experience of 18F-fluorocholine (FCho) and 18fluoro-L-phenylalanine (FDOPA) PET–MRI in paediatric/TYA neuro-oncology patients is presented. (3) Results: Hybrid PET–MRI shows promise in the evalua...
Source
#1Jennifer E. GainsH-Index: 10
#2Matthew D. Aldridge (UCLH: University College London Hospitals NHS Foundation Trust)H-Index: 5
Last. Mark N. GazeH-Index: 28
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PURPOSE Iodine-131-labelled meta-iodobenzylguanidine (I-mIBG) and lutetium-177-labelled DOTATATE (Lu-DOTATATE) are used for molecular radiotherapy of metastatic neuroblastoma. These are taken up by the noradrenaline transporter (NAT) and the somatostatin receptor subtype 2 (SSTR-2), respectively. Scintigraphy of iodine-123-labelled meta-iodobenzylguanidine (I-mIBG) and gallium-68 DOTATATE (Ga-DOTATATE) PET are used to select patients for therapy. These demonstrate the extent and location of tumo...
3 CitationsSource
#2April-Louise Smith (UCLH: University College London Hospitals NHS Foundation Trust)H-Index: 1
Last. Mark N. GazeH-Index: 28
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Molecular radiotherapy, or targeted radionuclide therapy, uses systemically administered drugs bearing a suitable radioactive isotope, typically a beta emitter. These are delivered via metabolic or other physiological pathways to cancer cells in greater concentrations than to normal tissues. The absorbed radiation dose in tumour deposits causes chromosomal damage and cell death. A partner radiopharmaceutical, most commonly the same vector labelled with a different radioactive atom, with emission...
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#1Andrew Scarsbrook (Leeds Teaching Hospitals NHS Trust)H-Index: 29
#2David Bottomley (Leeds Teaching Hospitals NHS Trust)H-Index: 20
Last. Fergus V. Gleeson (University of Oxford)H-Index: 57
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Abstract Purpose Early and accurate localisation of lesions in patients with biochemical recurrence (BCR) of prostate cancer may guide salvage therapy decisions. The present study, XXX, aimed to evaluate the impact of 18F-fluciclovine on management of men with BCR of prostate cancer. Methods Men with a first episode of BCR following curative-intent primary therapy were enrolled at 6 UK sites. Patients underwent 18F-fluciclovine PET/CT according to standardised procedures. Clinicians documented m...
14 CitationsSource
#1Jennifer E. Gains (UCLH: University College London Hospitals NHS Foundation Trust)H-Index: 10
#2Veronica Moroz (University of Birmingham)H-Index: 10
Last. Mark N. Gaze (UCLH: University College London Hospitals NHS Foundation Trust)H-Index: 28
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PURPOSE: The objective of this phase IIa, open-label, single-centre, single-arm, two-stage clinical trial was to evaluate the safety and activity of 177-lutetium DOTATATE (LuDO) molecular radiotherapy in neuroblastoma. METHODS: Children with relapsed or refractory metastatic high-risk neuroblastoma were treated with up to four courses of LuDO. The administered activity was 75 to 100 MBq kg(-1) per course, spaced at 8- to 12-week intervals. Outcomes were assessed by the International Neuroblastom...
6 CitationsSource
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#1Asim AfaqH-Index: 14
#2Fergus V. GleesonH-Index: 57
Last. Jamshed Bomanji (UCLH: University College London Hospitals NHS Foundation Trust)H-Index: 12
view all 14 authors...
The purpose of these guidelines is to assist specialists in Nuclear Medicine and Radionuclide Radiology in recommending, performing, interpreting and reporting 18F-fluciclovine PET/computed tomography. It should be recognised that adherence to the guidance in this document will not assure an accurat
2 CitationsSource