Negar Bidar
AnalyteMolecular beaconCancerBiophysicsDownregulation and upregulationOligonucleotidemicroRNAAntigenAntibodyBiosensorChemistryDNA methylationEpitopeNucleic acidIn silicoPerineural invasionImmunotherapyLymphomaMolybdenum carbideCardiovascular problemsMethylationAntibody-dependent cell-mediated cytotoxicityComputer scienceCancer researchNucleotideMonoclonal antibodyCarcinogenesisMolecular engineeringComputational biologyText miningMedicineBiomarker (medicine)BiologyImmune systemFluorescence
5Publications
3H-index
11Citations
Publications 5
Newest
#1Negar BidarH-Index: 3
#2Tayebeh Rezaei (Tabriz University of Medical Sciences)H-Index: 4
Last. Behzad Baradaran (Tabriz University of Medical Sciences)H-Index: 41
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Gastric cancer (GC) is one of the leading causes of cancer-related death worldwide, due to poor prognosis and treatment failure; demanding new diagnostic and therapeutic targets. Therefore, in the present study, the methylation and expression status of ZNF677, as a promising tumor suppressor, were investigated in GC. Gene Expression Omnibus (GEO) datasets were used to initially evaluate ZNF677 expression and methylation in GC samples. Confirmation was performed on fifty internal samples, includi...
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#2Mohammad AminiH-Index: 4
Last. Ahad MokhtarzadehH-Index: 33
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#2Saeed Khalili (SRTTU: Shahid Rajaee Teacher Training University)H-Index: 15
Last. Michael R. Hamblin (Harvard University)H-Index: 128
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Abstract Bispecific antibodie (BsAbs) combine two or more epitope-recognizing sequences into a single protein molecule. The first therapeutic applications of BsAbs were focused on cancer therapy. However, these antibodies have grown to cover a wider disease spectrum, including imaging, diagnosis, prophylaxis, and therapy of inflammatory and autoimmune diseases. BsAbs can be categorized into IgG-like formats and non-IgG-like formats. Different technologies have been used for the construction of B...
3 CitationsSource
#1Negar BidarH-Index: 3
#2Mohammad Amini (Tabriz University of Medical Sciences)H-Index: 4
Last. Miguel de la Guardia (University of Valencia)H-Index: 66
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Abstract The improvement of nucleic acid probes as vital molecular engineering devices will cause a noteworthy contribution to developments in bioimaging, biosensing, and disorders diagnosis. The molecular beacon (MB) which was designed by Tyagi and Kramer in 1996, are loop-stem hairpin-designed oligonucleotides armed with a quencher and a dye (also named reporter groups) at the 3´ or 5´ ends. This construction allows that MBs in the absence of their target complementary molecules do not fluores...
3 CitationsSource
#1Negar BidarH-Index: 3
#2Fatemeh OroojalianH-Index: 15
Last. Miguel de la Guardia (University of Valencia)H-Index: 66
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Abstract Micro ribose nucleic acid (miRNA) recognition is of remarkable significance in the investigation of its functions as well as diagnosis of various diseases. The significance of miRNA itself is owing to the complex regulatory roles in several physiological processes and its close association with important diseases such as cardiovascular problems, diabetes, Alzheimer’s disease and different kinds of cancers. On the other hand, there are numerous challenges to conquer in the recognition of...
7 CitationsSource