Zakia Azmani
Erasmus University Rotterdam
GeneCD3CancerCellMolecular biologyTranscriptomeGene expression profilingComplementary DNABisulfite sequencingDNA methylationT cellFetal hemoglobinLiquid biopsyHBG1HBG2Hereditary persistence of fetal hemoglobinCirculating Cell-Free DNAMethylationEpigeneticsDNA sequencingDNAFlow cytometryHaploinsufficiencyCell cultureChromatinBiology
3Publications
1H-index
0Citations
Publications 5
Newest
#1T. Deger (EUR: Erasmus University Rotterdam)H-Index: 1
#2Ruben Boers (EUR: Erasmus University Rotterdam)H-Index: 4
Last. Lisanne F. van Dessel (EUR: Erasmus University Rotterdam)H-Index: 3
view all 16 authors...
BACKGROUND DNA methylation detection in liquid biopsies provides a highly promising and much needed means for real-time monitoring of disease load in advanced cancer patient care. Compared to the often-used somatic mutations, tissue- and cancer-type specific epigenetic marks affect a larger part of the cancer genome and generally have a high penetrance throughout the tumour. Here, we describe the successful application of the recently described MeD-seq assay for genome-wide DNA methylation profi...
Source
#1Fleur van der Sijde (EUR: Erasmus University Rotterdam)H-Index: 4
#2Zakia Azmani (EUR: Erasmus University Rotterdam)H-Index: 1
Last. Quisette P Janssen (EUR: Erasmus University Rotterdam)H-Index: 4
view all 0 authors...
Background:Biomarkers predicting treatment response may be used to stratify pancreatic ductal adenocarcinoma (PDAC) patients for therapy. The aim of this study was to identify circulating tumor DNA...
Source
#1T. Deger (EUR: Erasmus University Rotterdam)H-Index: 1
#2Ruben Boers (EUR: Erasmus University Rotterdam)H-Index: 4
Last. L. F. van Dessel (EUR: Erasmus University Rotterdam)
view all 16 authors...
BackgroundDNA methylation detection in liquid biopsies provides a highly promising and much needed means for real-time monitoring of disease load in advanced cancer patient care. Compared to the often-used somatic mutations, tissue- and cancer-type specific epigenetic marks affect a larger part of the cancer genome and generally have a high penetrance throughout the tumour. Here we describe the successful application of the recently described MeD-seq assay for genome-wide DNA methylation profili...
Source
#1Marja W. WesselsH-Index: 34
#2Marjon H. CnossenH-Index: 24
Last. Sjaak PhilipsenH-Index: 45
view all 18 authors...
The BCL11A gene encodes a transcriptional repressor with essential functions in multiple tissues during human development. Haploinsufficiency for BCL11A causes Dias-Logan syndrome (OMIM 617101), an intellectual developmental disorder with hereditary persistence of fetal hemoglobin (HPFH). Due to the severe phenotype, disease-causing variants in BCL11A occur de novo. We describe a patient with a de novo heterozygous variant, c.1453G>T, in the BCL11A gene, resulting in truncation of the BCL11A-XL ...
Source
#1Nicolle H.R. Litjens (EUR: Erasmus University Rotterdam)H-Index: 27
#2Anton W. Langerak (EUR: Erasmus University Rotterdam)H-Index: 58
Last. Wilfred F. J. van IJcken (EUR: Erasmus University Rotterdam)H-Index: 69
view all 10 authors...
Transcriptomics can be combined with TRA and TRB clonotype analysis at the single cell level. The aim of this study was to validate this approach on the ICELL8 Single-Cell system and to evaluate its usefulness to analyse clinical paucicellular samples. For this purpose, we carefully selected T cell lines with defined TRA/TRB clonotypes as well as clinical samples enriched for CD3+ T cells that possess a complex TCR repertoire. Low cell numbers of the different samples were dispensed in a chip on...
Source
Close Researchers
Wilfred F. J. van IJcken
H-index : 69
Erasmus University Medical Center
Rutger W W Brouwer
H-index : 21
Erasmus University Medical Center
Ryo Kurita
H-index : 24
Kyushu University
Dirk J. Grünhagen
H-index : 29
Erasmus University Rotterdam
Marja W. Wessels
H-index : 34
Erasmus University Rotterdam
Mariska Klepper
H-index : 13
Erasmus University Rotterdam
Thamar B. van Dijk
H-index : 23
Erasmus University Rotterdam
Joost Gribnau
H-index : 29
Erasmus University Rotterdam
Stella A. de Man
H-index : 5
Erasmus University Rotterdam
Marjon H. Cnossen
H-index : 24
Boston Children's Hospital
V. de Weerd
H-index : 2
Erasmus University Rotterdam
Stefan Sleijfer
H-index : 60
Erasmus University Rotterdam
Rolph Pfundt
H-index : 62
Radboud University Nijmegen
Mirjam C. G. N. van den Hout
H-index : 11
Erasmus University Rotterdam
Nicolle H.R. Litjens
H-index : 27
Erasmus University Rotterdam
Anton W. Langerak
H-index : 58
Erasmus University Rotterdam
Saskia M. Wilting
H-index : 26
Erasmus University Rotterdam
Kirsten van Lom
H-index : 17
Erasmus University Rotterdam
Nynke Gillemans
H-index : 22
Erasmus University Rotterdam
Sjaak Philipsen
H-index : 45
Erasmus University Rotterdam
T. Deger
H-index : 1
Erasmus University Rotterdam
Maaike de Bie
Erasmus University Rotterdam
K. L. Juliëtte Schmidt
H-index : 1
Amy C. J. van der List
Erasmus University Rotterdam
Cees Verhoef
H-index : 30
Erasmus University Rotterdam
Lindsay Angus
H-index : 7
Erasmus University Rotterdam
Steven M. Coyne
H-index : 2
Harvard University
Joachim Boers
H-index : 4
Erasmus University Rotterdam
Ruben Boers
H-index : 4
Erasmus University Rotterdam
Martijn P. Lolkema
H-index : 17
Erasmus University Rotterdam
Yukio Nakamura
H-index : 38
Shinshu University
Divya S. Vinjamur
H-index : 8
Harvard University
Jwm Martens
H-index : 6
Erasmus University Rotterdam
Alexander T. den Dekker
H-index : 2
Erasmus University Rotterdam
W F J van IJcken
H-index : 13
Erasmus University Rotterdam
L. F. van Dessel
Erasmus University Rotterdam
M. M. van der Put
Erasmus University Rotterdam
Johanna W. Wilmink
H-index : 29
University of Amsterdam
Leonie J. M. Mekenkamp
H-index : 14
Medisch Spectrum Twente
Marc G. Besselink
H-index : 88
University of Amsterdam
Bert A. Bonsing
H-index : 43
Leiden University Medical Center
Bas Groot Koerkamp
H-index : 41
Erasmus University Rotterdam
Marjolein Y.V. Homs
H-index : 17
Erasmus University Rotterdam
Michiel G. H. Betjes
H-index : 62
Erasmus University Rotterdam
Eveline E. Vietsch
H-index : 2
Erasmus University Rotterdam
Fleur van der Sijde
H-index : 4
Erasmus University Rotterdam
Quisette P Janssen
H-index : 4
Erasmus University Rotterdam
Dana A. M. Mustafa
H-index : 12
Erasmus University Rotterdam
Brigitte C.M. Haberkorn
H-index : 2
Erasmus University Medical Center
Saskia A C Luelmo
H-index : 5
Leiden University Medical Center
Jan Willem B. de Groot
H-index : 25
Erasmus University Rotterdam
Ron H.N. van Schaik
H-index : 69
Erasmus University Medical Center
Casper H.J. van Eijck
H-index : 72
Erasmus University Rotterdam
Daniel E. Bauer
H-index : 49
Harvard University
This website uses cookies.
We use cookies to improve your online experience. By continuing to use our website we assume you agree to the placement of these cookies.
To learn more, you can find in our Privacy Policy.