Lorenzo Palagi
University of Turin
BioassayConjugated systemBiophysicsLiposomeChemistryMicrovesiclesCombinatorial chemistryNucleic acidIodobenzeneLithium iodideIodideDetection thresholdPhospholipid vesiclesPalladiumCatalytic cycleBiology
Publications 3
#1Lorenzo Palagi (UNITO: University of Turin)H-Index: 2
#2Enza Di Gregorio (UNITO: University of Turin)H-Index: 16
Last. Eliana Gianolio (UNITO: University of Turin)H-Index: 37
view all 8 authors...
The search for alternatives to Gd-containing magnetic resonance imaging (MRI) contrast agents addresses the field of Fe(III)-bearing species with the expectation that the use of an essential metal ion may avoid the issues raised by the exogenous Gd. Attention is currently devoted to highly stable Fe(III) complexes with hexacoordinating ligands, although they may lack any coordinated water molecule. We found that the hexacoordinated Fe(III) complex with two units of deferasirox, a largely used ir...
#1Jacopo SforziH-Index: 2
#2Lorenzo PalagiH-Index: 2
Last. Silvio AimeH-Index: 94
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This review highlights the potential of using liposomes in bioassays. Liposomes consist of nano- or micro-sized, synthetically constructed phospholipid vesicles. Liposomes can be loaded with a number of reporting molecules that allow a dramatic amplification of the detection threshold in bioassays. Liposome-based sensors bind or react with the biological components of targets through the introduction of properly tailored vectors anchored on their external surface. The use of liposome-based formu...
#1Stefano Parisotto (UNITO: University of Turin)H-Index: 6
#2Lorenzo Palagi (UNITO: University of Turin)H-Index: 2
Last. Annamaria Deagostino (UNITO: University of Turin)H-Index: 21
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: Palladium(0)-catalysed hydro-alkylation or -alkenylation of alkoxyallenes with N-tosylhydrazones gives direct access to conjugated and skipped 1-alkoxydienes with high efficiency and excellent functional-group compatibility. The reaction is proposed to involve the in situ-formed t-butanol as proton source in the key step of the allylpalladium(II) species generation. Moreover, lithium iodide or iodobenzene are employed as an unprecedented iodide (I- ) reservoir to sustain the catalytic cycle.
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