Chang-Ming Huang
Fujian Medical University
DissectionCancerInternal medicineDownregulation and upregulationSurgeryPathologymicroRNARegression analysisRetrospective cohort studyRandomized controlled trialSuppressorMortality rateStage (cooking)Prospective cohort studyCohort studyIntention-to-treat analysisClinical endpointSpecialtyHazard ratioPathologicalInstitutional review boardAdjuvantMetastasisCDK5RAP3LymphLaparoscopyEzrinGastrectomyLymphadenectomyLymph nodeOncogeneIndocyanine greenPopulationSplenic Hilar Lymph NodeEarly Gastric CancerStomach neoplasmCell cycleCancer surgeryPostoperative complicationCurvatures of the stomachCancer researchProportional hazards modelClinical trialGeneral surgeryInformed consentMedicineBiomarker (medicine)Biology
Publications 9
#1Jia-Bin WangH-Index: 21
Last. Mi LinH-Index: 22
view all 18 authors...
#1Changming HuangH-Index: 1
#1Chang-Ming HuangH-Index: 2
Last. Guoxin Li (Southern Medical University)H-Index: 33
view all 23 authors...
BACKGROUND: It is not clear whether laparoscopic and open distal gastrectomy produce similar outcomes in patients with locally advanced gastric cancer. Data from a multicenter, randomized, controlled trial (CLASS-01) showed that laparoscopic distal gastrectomy did not result in inferior disease-free survival at 3 years compared with open distal gastrectomy. Here, we present 5-year overall survival data from this trial. METHODS: From September 2012 through December 2014, we randomly assigned 1056...
#1Qi-Yue ChenH-Index: 23
#2Jian-Wei XieH-Index: 23
Last. Chang-Ming HuangH-Index: 2
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Importance The application of indocyanine green (ICG) imaging in laparoscopic radical gastrectomy is in the preliminary stages of clinical practice, and its safety and efficacy remain controversial. Objective To investigate the safety and efficacy of ICG near-infrared tracer-guided imaging during laparoscopic D2 lymphadenectomy in patients with gastric cancer. Design, Setting, and Participants Patients with potentially resectable gastric adenocarcinoma (clinical tumor stage cT1-cT4a, N0/+, M0) w...
16 CitationsSource
#1Jian-Xian Lin (Fujian Medical University)H-Index: 22
#2Ping Li (Fujian Medical University)H-Index: 25
Last. Chao-Hui Zheng (Fujian Medical University)H-Index: 21
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Background: The splenic hilar lymph node (No. 10 LN) dissection is still controversial for patients with advanced proximal gastric cancer (APGC) not invading the greater curvature. The present study aimed to evaluate the short-term outcomes of laparoscopic spleen-preserving No. 10 lymphadenectomy (LSPL) for APGC not invading the greater curvature and the characteristic of No. 10 LN metastasis. Methods: This single-center, open-label, randomized, phase III clinical trial was done in the Departmen...
#1Zhouqiao Wu (PKU: Peking University)H-Index: 13
#2Hui-Min Cheng (CUFE: Central University of Finance and Economics)H-Index: 4
Last. Jiafu Ji (PKU: Peking University)H-Index: 45
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Background: The objective of this study is to identify independent risks and protective factors and to construct a mortality prediction model for gastrectomy in the Chinesepopulation. Study design: This is a population-based prospective cohort at an institutional level. Seventy-two participating hospitals reported their annual gastrectomy data between 2014 and 2016, while 44 variables covering the institution and surgical information were included in the analysis. We used R software to encode an...
#2Zu-Kai WangH-Index: 4
Last. Ping Li
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#1Chao-Hui Zheng (Fujian Medical University)H-Index: 21
#2Yan-Chang Xu (Fujian Medical University)H-Index: 2
Last. Chang-Ming HuangH-Index: 2
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Background: Previous retrospective studies have shown that laparoscopic spleen-preserving D2 total gastrectomy (LSTG) for advanced upper third gastric cancer (AUTGC) is safe. However, all previous studies were underpowered. We therefore conducted a prospective, multicenter, single-arm, phase II study to evaluate the feasibility of LSTG in patients with AUTGC. Methods: Between September 2016 and October 2017, 251 patients with newly diagnosed AUTGC (cT2-4a, N-/ , M0) underwent LSTG at 19 institut...
#1Yanfeng Hu (Southern Medical University)
#1Yanfeng Hu (Southern Medical University)H-Index: 22
Last. Guoxin Li (Southern Medical University)H-Index: 33
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Background Laparoscopy-assisted gastrectomy (LAG) has been indicated to be safe, feasible, and oncologically efficacious for the treatment of early gastric cancer by both retrospective and prospective studies. Although some reports have demonstrated that LAG was also a safe and technically feasible procedure for advanced gastric cancer (AGC), its oncologic outcomes have not yet been confirmed in a multicenter, large-scale study. The aim of this study was to evaluate the oncologic outcomes of LAG...
51 CitationsSource
#1Long-Long CaoH-Index: 20
#2Jian-Wei XieH-Index: 23
Last. Chang-Ming HuangH-Index: 2
view all 10 authors...
miR-183, a member of an evolutionarily conserved miRNA cluster (miR-96, miR-182, and miR-183), has been demonstrated to act as both a tumor suppressor and oncogene in various type of human cancer. However, the biological role of miR-183 in gastric cancer (GC) still remains unclear. In the present study, miR-183 expression was significantly decreased in gastric cancer tissues compared with its' adjacent normal tissues, and down-regulation of miR-183 was significantly associated with lymph node me...