Hossein Rahimi
Zanjan University of Medical Sciences
ProdrugRisk analysis (engineering)CancerTargeted drug deliveryDrug carrierCas9Genome editingGenome engineeringBlood proteinsNanomedicineNanotechnologyChemistryAlbuminChemotherapyCoronavirusDrug deliveryEmerging infectious diseaseDrugDiagnostic systemIntracellular organellesDelivery methodsViral infection2019-20 coronavirus outbreakSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)Limited accessDiagnosis treatmentEffective treatmentHighly skilledControlled deliveryWhole bodyComputer scienceComputational biologyMedicinePandemicCRISPRPharmacology
5Publications
2H-index
14Citations
Publications 4
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#1Hamid Rashidzadeh (Zanjan University of Medical Sciences)H-Index: 5
#2Hossein Danafar (Zanjan University of Medical Sciences)H-Index: 30
Last. Mehdi Mirsaeidi (UM: University of Miami)H-Index: 32
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Coronavirus 2019 (COVID-19), as an emerging infectious disease, has caused significant mortality and morbidity along with socioeconomic impact. No effective treatment or vaccine has been approved yet for this pandemic disease. Cutting-edge tools, especially nanotechnology, should be strongly considered to tackle this virus. This review aims to propose several strategies to design and fabricate effective diagnostic and therapeutic agents against COVID-19 by the aid of nanotechnology. Polymeric, i...
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#1Hossein Rahimi (Zanjan University of Medical Sciences)H-Index: 2
#2Marziyeh Salehiabar (Tabriz University of Medical Sciences)H-Index: 10
Last. João Conde (NOVA: Universidade Nova de Lisboa)H-Index: 33
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The emergence of the new coronavirus 2019 (COVID-19) was first seen in December 2019, which has spread rapidly and become a global pandemic. The number of cases of COVID-19 and its associated mortality have raised serious concerns worldwide. Early diagnosis of viral infection undoubtedly allows rapid intervention, disease management, and substantial control of the rapid spread of the disease. Currently, the standard approach for COVID-19 diagnosis globally is the RT-qPCR test; however, the limit...
5 CitationsSource
#1Hossein Rahimi (Zanjan University of Medical Sciences)H-Index: 2
#2Marziyeh Salehiabar (Tabriz University of Medical Sciences)H-Index: 10
Last. Thomas J. Webster (NU: Northeastern University)H-Index: 104
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Abstract Exploiting bacterial DNA-acting enzymes and expanding their repertoire for genome engineering have been major technological and conceptual advances in molecular biology over the last decade. The CRISPR-Cas9 system offers many attractive superiorities, such as multiplexing, high precision, low cost, and simplicity compared to other strategies/systems/approaches known to date for gene editing. The efficient co-delivery of Cas9 and single guide RNA(s) into a desired cell and subsequent cor...
7 CitationsSource
#1Hossein Rahimi (Zanjan University of Medical Sciences)H-Index: 2
#2Marziyeh Salehiabar (Tabriz University of Medical Sciences)H-Index: 10
Last. Hamed Nosrati (Zanjan University of Medical Sciences)H-Index: 19
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Proteins have been used to fabricate and design carriers for systemic drug delivery. One of the proteins that shows great potential for the applications in systemic delivery is albumin which is the most abundant plasma protein. This protein has been widely used in nanotechnology-based treatments of many diseases as a promising drug carrier. Taking cancer, an age-associated disease, as an example, the use of albumin nanoparticles as a drug carrier overcomes some of the limitations of chemotherapy...
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