Thomas C. Varkey
University of Texas at Austin
Evidence-based practiceDermatologyRandomized controlled trialPolitical scienceIntensive care medicinePediatricsMultidisciplinary approachOptic neuritisImmunotherapyLungCollapse (medical)Vaccine failureDiseaseMEDLINERespiratory tractContext (language use)Trigeminal neuralgiaMultiple sclerosisIntervention (counseling)PanicNatalizumabMethotrexateRegimenPopulationCase conferenceNeurology clinicFacial painSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)Clinical courseResistance (psychoanalysis)Public relationsAdversaryMedicinePandemic
5Publications
2H-index
34Citations
Publications 6
Newest
Abstract The COVID-19 pandemic has devastated individuals, families, and institutions throughout the world. Despite the breakneck speed of vaccine development, the human population remains at risk of further devastation. The decision to not become vaccinated, the protracted rollout of available vaccine, vaccine failure, mutational forms of the SARS virus, which may exhibit mounting resistance to our molecular strike at only one form of the viral family, and the rapid ability of the virus(es) to ...
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#3Thomas C. Varkey (KP: Kaiser Permanente)H-Index: 2
#4Robert P. Lisak (KP: Kaiser Permanente)H-Index: 1
Last. Scott Newsome (KP: Kaiser Permanente)H-Index: 1
view all 10 authors...
A 31-year-old woman presented with fever, ataxia, double vision, confusion, and auditory hallucinations, preceded by 2 weeks of cough, increased oral secretions, and dermatomal rash. Her medical history was unremarkable. Her family history was notable for first-degree relatives with autoimmune
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#2Nick Hogan (University of Texas at Austin)H-Index: 1
Last. Teresa C. FrohmanH-Index: 37
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The patient is a right-handed White woman with relapsing-remitting MS diagnosed subsequent to left acute optic neuritis (AON). She described a previous transient episode of severe, electrical, and paroxysmal facial pain consistent with trigeminal neuralgia. Initial MRI demonstrated supratentorial
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#1Nidhiben Anadani (UR: University of Rochester)
#2Megan HylandH-Index: 5
Last. Teresa Frohman (UR: University of Rochester)H-Index: 1
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A 38-year-old woman with MS receiving natalizumab presented to the neurology clinic with the complaint of a new neurologic symptom. ### Clinical course The patient had a 6-year history of clinically stable MS, albeit exhibiting radiographic progression despite strict adherence to daily
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#1Elliot M. Frohman (University of Texas at Austin)H-Index: 84
#2Nicole R. Villemarette-Pittman (LSU Health Sciences Center New Orleans)H-Index: 14
Last. Teresa C. Frohman (University of Texas at Austin)H-Index: 37
view all 10 authors...
Abstract Here, in Part II of a duology on the characterization and potential treatment for COVID-19, we characterize the application of an innovative treatment regimen for the prevention of the transition from mild to severe COVID-19, as well as detail an intensive immunotherapy intervention hypothesis. We propose as a putative randomized controlled trial that high-dose methotrexate with leucovorin (HDMTX-LR) rescue can abolish ‘PANIC’, thereby ‘left-shifting’ severe COVID-19 patients to the gro...
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#1Elliot M. Frohman (University of Texas at Austin)H-Index: 84
#2Nicole R. Villemarette-Pittman (LSU Health Sciences Center New Orleans)H-Index: 14
Last. Teresa C. Frohman (University of Texas at Austin)H-Index: 37
view all 9 authors...
Abstract The COVID-19 pandemic has produced a world-wide collapse of social and economic infrastructure, as well as constraining our freedom of movement. This respiratory tract infection is unprecedented in that it targets the most distal and highly vulnerable aspect of the human bronchopulmonary tree, specifically, the alveoli that are responsible for the loading of oxygen upon red cell hemoglobin for use by all of the body's tissues. In most symptomatic individuals, the reaction is a productiv...
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