Meng Wang
Jilin University
Lithotomy positionCancerRadiologyDownregulation and upregulationMajor duodenal papillaSurgeryPathologyDNA damageCD28Retrospective cohort studyCD8HEK 293 cellsMortality rateStage (cooking)ChemistryApoptosisIn vivoPancreatitisBiliary tractLaparoscopic surgeryLiver cancerCholecystectomyDuodenumCommon bile ductHepatolithiasisCystic ductCarcinomaFenestrationEndoscopyHemostasisSorafenibPancreasPortal vein thrombosisPortal hypertensionPancreaticoduodenectomyCommon hepatic ductTumor progressionBile ductAbdomenBlood transfusionLaparoscopyPancreatic cancerDifferential diagnosisVomitingSphincterPancreatic fistulaAdenocarcinomaEndoscopic nasobiliary drainageDuodenal stenosisMixed adenoneuroendocrine carcinomaTraumatic splenic ruptureStatistical analysisBlood lossEpigastric painLiver functionOperative mortalityPerioperative blood lossWorld healthPancreatic leakLaparoscopic splenectomyBiliary drainageOpen surgeryNeuroendocrine carcinomaSurgical resectionIncidence (epidemiology)Cancer researchClinical pathologyTransfectionFlow cytometryMAPK/ERK pathwayCell growthMedicineComplicationCell cultureBlotPI3K/AKT/mTOR pathwayBiologyPharmacologymTORC1c-Raf
12Publications
3H-index
22Citations
Publications 11
Newest
#1Chao Jiang (JLU: Jilin University)H-Index: 4
#2Xueyan Liu (JLU: Jilin University)H-Index: 2
Last. Meng Wang (JLU: Jilin University)H-Index: 3
view all 4 authors...
Paraduodenal pancreatitis (PP) is a rare type of focal pancreatitis involving the groove space. It mimics pancreatic head carcinoma, and its diagnosis and treatment are challenging. Pancreatoduodenectomy (PD) has traditionally been the primary surgical treatment for duodenal stenosis or suspected cancer.We herein report a case of PP in a 65-year-old man. The patient was admitted to the hospital for postprandial epigastric pain and vomiting. A low-density mass between the uncinate process of the ...
Source
#1Chao Jiang (JLU: Jilin University)H-Index: 4
#2Xueyan Liu (JLU: Jilin University)H-Index: 2
Last. Guangyi Wang (JLU: Jilin University)H-Index: 16
view all 5 authors...
: miR-802 has been reported to be dysregulated in multiple tumors and contribute to tumor progression. However, its role in HCC was still largely unknown. The aim of this study is to investigate the function and mechanism of miR-802 in HCC progression. The results showed that miR-802 was upregulated in the peripheral blood and tumor tissue of HCC patients, and high levels of blood miR-802 predicted poor prognosis. miR-802 had no effect on the proliferation and migration of HCC cell lines. Intere...
9 CitationsSource
#1Hai-Wen Zhang (JLU: Jilin University)H-Index: 3
#2Kai Kou (JLU: Jilin University)H-Index: 3
Last. Guangyi Wang (JLU: Jilin University)H-Index: 16
view all 8 authors...
BackgroundThe concept of mixed adenoneuroendocrine carcinoma (MANEC) was introduced in the 2010 World Health Organization classification of digestive neuroendocrine neoplasms. Bile duct invasion by...
4 CitationsSource
#1Meng Wang (JLU: Jilin University)H-Index: 3
#2Guoyue Lv (JLU: Jilin University)H-Index: 15
Last. Guangyi Wang (JLU: Jilin University)H-Index: 16
view all 5 authors...
Hepatocellular carcinoma (HCC) is the most common liver cancer and has a poor prognosis. miR-302a is an important regulator of tumor occurrence and deterioration, while MAP3K2 and PBX3 genes are involved in cancer cell proliferation and apoptosis. In this study, the expression of miR-302a and MAP3K2/PBX3 were evaluated by qPCR in liver cancer cell lines. Next, the target relationship between miR-302a and MAP3K2/PBX3 was verified using luciferase assays. Meanwhile, the expression correlation betw...
11 CitationsSource
#1Meng Wang (JLU: Jilin University)H-Index: 3
view all 5 authors...
Objective To summarize the efficacy and feasibility of laparoscopic splenectomy combined with selective pericardial devascularization for cirrhotic portal hypertension. Methods From January 2015 to January 2017, the clinical data of 29 cases of cirrhotic portal hypertension treated by laparoscopic splenectomy combined with selective pericardial devascularization were analyzed retrospectively. Results Laparoscopic surgery was successful in all but one cases, who was converted to open surgery. The...
Source
#1Meng Wang (JLU: Jilin University)H-Index: 3
Last. Junfeng YeH-Index: 1
view all 6 authors...
Objective To investigate the indications and clinical effect of emergency laparoscopic splenectomy for traumatic splenic rupture. Methods Clinical data of 30 traumatic splenic rupture patients undergoing emergency laparoscopic splenectomy from Aug 2011 to Mar 2016 in our hospital were analyzed retrospectively. Results All patients were of simple traumatic spleen rupture without combined injuries. There were 2 cases of grade Ⅱ (6.7%), 17 cases of grade Ⅲ (56.7%), 10 cases of grade Ⅳ (33.3%), 1 ca...
Source
#1Xiaodong Sun (JLU: Jilin University)H-Index: 1
#2Wei QiuH-Index: 5
view all 5 authors...
Objective To investigate the indications and clinical efficacy of combined application of laparoscope, choledochoscope and duodenoscope in the treatment of extrahepatic cholangiolithiasis. Methods The retrospective cohort study was adopted. The clinical data of 2 364 patients with extrahepatic cholangiolithiasis who were admitted to the First Hospital of Jilin University from January 2008 to December 2015 were collected. Of the 2 364 patients, 861 patients had cholecystolithiasis combined with e...
Source
#1Feng Wei (JLU: Jilin University)H-Index: 1
#2Ping ZhangH-Index: 1
Last. Guangyi WangH-Index: 1
view all 5 authors...
Objective To investigate the molecular mechanism of pancreatic cancer cell resistance to mammalian target of rapamycin( mTOR) inhibitor RAD001,and explore a feasible therapeutic strategy to overcome the resistance in patients with pancreatic cancer. Methods Western blotting was conducted to find out whether RAD001 induced c-Raf-ERK feedback activation and to identify whether RAD001 in combination with c-Raf inhibitor sorafenib could effectively block the feedback activation of c-Raf and downstre...
1 Citations
#1Meng Wang (JLU: Jilin University)H-Index: 3
#2Guangyi Wang (JLU: Jilin University)H-Index: 16
Last. Ping Zhang (JLU: Jilin University)H-Index: 1
view all 4 authors...
Objective To analyze the significant impact factors of postoperative hemorrhage after pancreaticoduodenectomy.Method The clinical data of 154 patients who underwent pancreatieoduodeneetomy from Jan.2009 to Jun.2012 were retrospectively analyzed.Results The incidence of postoperative hemorrhage was 10.4% (16/154).The mortality caused by this complication was 12.5% (2/16).Among these patients,intra-abdominal hemorrhage occurred in seven patients,and gastrointestinal hemorrhage occurred in nine pat...
Source
#1Meng Wang (JLU: Jilin University)H-Index: 3
#2Guang-yi Wang (JLU: Jilin University)H-Index: 1
Last. Ya-jun Geng (JLU: Jilin University)
view all 5 authors...
Objectiye To investigate the clinical application value of emergency therapeutic encoscopic retrograde cholangio-pancreatography (ERCP) on acute biliary-pancreatic diseases.Methods Duodenoscope was applied on the emergency treatment for 103 patients of acute biliary-pancreatic diseases from March 2007 to May 2010. According to patients' conditions, the examination of ERCP,endoscopic nasobiliary drainage (ENBD) and endoscopic sphincterotomy (EST) were carried out. The papilla sphincter was sliver...
Source