Bei Wang
China Three Gorges University
CancermicroRNALung cancerTumor suppressor geneNasopharyngeal carcinomaMetastasisPancreatic cancerBladder cancerOvarian cancerOncogeneCancer researchColorectal cancerBreast cancerCarcinogenesisLong non-coding RNASignal transductionMedicineProtein kinase BPI3K/AKT/mTOR pathwayBiologyCancer cell
9Publications
2H-index
6Citations
Publications 14
Newest
#1Juanjuan Zhong (CTGU: China Three Gorges University)
#2Jinlan Chen (CTGU: China Three Gorges University)H-Index: 1
Last. Chengfu Yuan (CTGU: China Three Gorges University)H-Index: 13
view all 8 authors...
BACKGROUND It is substantiated that LncRNAs are associated with carcinoma progression. OIP5-AS1 is a tumor-related carcinoma suppressor lncRNA, previously discovered in zebrafish, which is involved in the progression of a variety of cancers, has a regulatory effect on carcinoma, and interacts with miRNA and other biomolecules to affect the physiological and pathological processes of carcinoma cells. This article will discuss the effect of OIP5-AS1 in various cancers and its regulatory mechanism....
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#1Qi Zhang (CTGU: China Three Gorges University)
#2Yinxin Wu (CTGU: China Three Gorges University)
Last. Chengfu Yuan (CTGU: China Three Gorges University)H-Index: 13
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Background null MBNL1, a protein encoded by q25 gene on chromosome 3, belongs to the tissue-specific RNA metabolic regulation family, which controls RNA splicing.[1]MBNL1 formed in the process of development drive large transcriptomic changes in cell differentiation,[2] it serves as a kind of tumor differentiation inhibitory factor.MBNL1 has a close relationship with cancer, comprehensive analysis, [3]found that breast cancer, leukemia, stomach cancer, esophageal adenocarcinoma, glial cell carci...
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#1Wen Xu (CTGU: China Three Gorges University)H-Index: 2
#2Bei Wang (CTGU: China Three Gorges University)H-Index: 2
Last. Chengfu Yuan (CTGU: China Three Gorges University)H-Index: 13
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BACKGROUND Long noncoding RNA (lncRNA) fetal-lethal non-coding developmental regulatory RNA (FENDRR), a newly known lncRNA, has been reported to be abnormally expressed in diverse tumors. This review is focused on clarifying the mechanism of FENDRR to regulate the biological process of tumors, affirming its value as a target for tumor therapy. METHODS The pathophysiological mechanism of FENDRR acting on tumors has been analyzed and summarized by reviewing PubMed. RESULTS The expression of lncRNA...
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#1Chengyu Hu (CTGU: China Three Gorges University)H-Index: 2
#2Wen Xu (CTGU: China Three Gorges University)H-Index: 2
Last. Chengfu Yuan (CTGU: China Three Gorges University)H-Index: 13
view all 7 authors...
Background null Long non-coding RNAs (lncRNAs) has no protein-coding potential due to the lack of an apparent open reading frame. There is growing evidence that lncRNA DGCR5 has a vital regulatory role in human illnesses' pathological development, particularly in the digestive system's carcinogenesis and progression. Abnormal DGCR5 expression affects different cellular functions such as proliferation, aggression, and metastasis. This paper aims to probe into the pathophysiological functions and ...
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#1Bei Wang (CTGU: China Three Gorges University)H-Index: 2
#2Wen Xu (CTGU: China Three Gorges University)H-Index: 2
Last. Chengfu Yuan (CTGU: China Three Gorges University)H-Index: 13
view all 7 authors...
BACKGROUND Long non-coding RNAs (lncRNA) have influenced numerous biology processes, which has provoked great interest. Not only that, LncRNA DUXAP8 mediates tumorigenesis by affecting the activity of miRNAs, signaling pathways, and oncogene. METHODS The functions of DUXAP8 have been summarized by reading relevant articles on PubMed. RESULTS lncRNA DUXAP8 acts oncogene in most tumors. The abnormal over-expression is associated with the proliferation, invasion, migration, anti-autophagy of tumors...
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#1Yuxuan Cai (CTGU: China Three Gorges University)H-Index: 1
#2Bei Wang (CTGU: China Three Gorges University)H-Index: 2
Last. Chengfu Yuan (CTGU: China Three Gorges University)H-Index: 13
view all 9 authors...
BACKGROUND Endometrial cancer is the fourth most common malignancy in the female population worldwide. It was estimated that 65,620 new cases and 12,590 subsequent deaths occurred in 2020 in the United States. Patients with type II and advanced endometrial cancer do not respond well to the current treatments. Therefore, endometrial cancer should be better understood in order to develop more effective treatments. OBJECTIVE To provide an overview of genetic, metabolic characteristics, therapeutic ...
1 CitationsSource
#1Bei Wang (CTGU: China Three Gorges University)H-Index: 2
#2Wen Xu (CTGU: China Three Gorges University)H-Index: 2
Last. Chengfu Yuan (CTGU: China Three Gorges University)H-Index: 13
view all 7 authors...
BACKGROUND Long non-coding RNA (lncRNA) breast cancer anti-estrogen resistance 4 (BCAR4) is a characterized oncogenic lncRNA in different cancers. This review is dedicated to summarize various molecular mechanisms of BCAR4 and demonstrate that the biological functions exerted by BCAR4 are good entry points for therapy. METHODS The molecular mechanism of BCAR4 acting on tumors is summarized by reviewing PubMed. RESULTS The expression of lncRNA BCAR4 is abnormally increased in all kinds of tumors,...
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#1Wen Xu (CTGU: China Three Gorges University)H-Index: 2
#2Mengdan Ding (CTGU: China Three Gorges University)
Last. Chengfu Yuan (CTGU: China Three Gorges University)H-Index: 13
view all 6 authors...
Many experimental shreds of evidence have shown that lncRNA MALAT1 is related to proliferation ability, invasion and migration ability, autophagy ability, and chemoresistance in gastric cancer. Moreover, MALAT1 is related to metastasis and patient prognosis in gastric cancer. This review aims to reveal the biological functions and specific mechanisms of MALAT1 in gastric cancer. METHODS After a comprehensive and systematic search in PubMed, various molecular mechanisms of MALAT1 in mediating gas...
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#1Wen Xu (CTGU: China Three Gorges University)H-Index: 2
#2Bei Wang (CTGU: China Three Gorges University)H-Index: 2
Last. Chengfu Yuan (CTGU: China Three Gorges University)H-Index: 13
view all 7 authors...
BACKGROUND Long non-coding RNAs (lncRNA) have been identified as novel molecular regulators in cancers. LncRNA ADAMTS9-AS2 can mediate the occurrence and development of cancer through various ways such as regulating miRNAs, activating the classical signaling pathways in cancer, and so on, which have been studied by many scholars. In this review, we summarize the molecular mechanisms of ADAMTS9-AS2 in different human cancers. METHODS Through a systematic search of PubMed, lncRNA ADAMTS9-AS2 media...
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#1Wen Xu (CTGU: China Three Gorges University)H-Index: 2
#2Bei Wang (CTGU: China Three Gorges University)H-Index: 2
Last. Chengfu Yuan (CTGU: China Three Gorges University)H-Index: 13
view all 6 authors...
BACKGROUND Long non-coding RNA (lncRNA) with little or no coding ability has shown a variety of biological functions in cancer, including epigenetic regulation, DNA damage, regulation of microRNAs, and participation in signal transduction pathways. LncRNA can be used as an oncogene and tumor suppressor gene through transcriptional regulation in cancer. For example, the over-expressed lncRNA DLEU2 promotes the occurrence of laryngeal cancer, lung cancer, hepatocellular carcinoma, etc. and inhibit...
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