Evianne L de Groot
Utrecht University
Internal medicineObstetricsRetrospective cohort studyFetusMedical recordUveitisAzathioprineCorticosteroidVisual acuityCholestasis of pregnancyPregnancyAdalimumabChoroidal neovascularizationMultifocal choroiditisPunctate inner choroidopathyPreventive therapyChoroiditisIn patientCorticosteroid treatmentPostpartum periodTreatment optionsDisease activityMedian timeRefractoryMedicine
Publications 3
#1Evianne L de Groot (UU: Utrecht University)H-Index: 1
#2Ramon A. C. van Huet (Radboud University Nijmegen)H-Index: 13
Last. Jeannette Ossewaarde-van Norel (UU: Utrecht University)H-Index: 9
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PURPOSE To evaluate the clinical course of idiopathic multifocal choroiditis (MFC) and punctate inner choroidopathy (PIC) and the efficacy and safety of treatment options during pregnancy. METHODS Patients with MFC or PIC and a pregnancy in 2011-2019 from two academic centres were enrolled. For the most recent pregnancy, data on best-corrected visual acuity (BCVA) before and after pregnancy, relapse rate in pregnancy and postpartum period and obstetric, maternal and neonatal outcomes were collec...
Abstract Purpose To evaluate the efficacy of adalimumab in patients with central multifocal choroiditis (cMFC) refractory to conventional corticosteroid-sparing immunomodulatory agents (IMT). Methods Medical records were reviewed from all patients with cMFC and treated with adalimumab with follow-up of at least 12 months. The study focused on the 12 months prior to and after the start of adalimumab. The imaging results were independently evaluated by two ophthalmologists. The main outcomes were ...
#1Evianne L de Groot (UU: Utrecht University)H-Index: 1
#2Ninette H. ten Dam-van Loon (UU: Utrecht University)H-Index: 9
Last. Jeannette Ossewaarde-van Norel (UU: Utrecht University)H-Index: 9
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PURPOSE: To evaluate the efficacy of corticosteroid-sparing immunomodulatory therapy (IMT) in patients with recurrent and/or sight-threatening central multifocal choroiditis (MFC). METHODS: This was a retrospective cohort study in a tertiary uveitis centre including all patients with MFC who have been treated with IMT for at least 12 months. Clinical data and imaging results were collected regarding the period prior to the start of IMT and at 3, 6, 12 and - where available - 24 months after the ...
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