Anacelia Ríos Quiroz
University of Basel
ParticleSignalOpticsPhysicsMicroscopyParticle sizeProtein particlesFlow imagingLight obscurationVolume concentration
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#1Anacelia Ríos Quiroz (University of Basel)H-Index: 1
#2Gabriela Québatte (University of Basel)H-Index: 6
Last. Michael AdlerH-Index: 11
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Although light obscuration is the “gold standard” for subvisible particle measurements in biopharmaceutical products, the current technology has limitations with respect to the detection of translucent proteinaceous particles and particles of sizes smaller and around 2 μm. Here, we describe the evaluation of a modified light obscuration sensor utilizing a novel measuring mode. Whereas standard light obscuration methodology monitors the height (amplitude) of the signal, the new approach monitors ...
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