Hina Shuto
RMIT University
Environmental chemistryIrradiationInternal medicineEndocrinologyDNA repairBehavioural despair testDNA damageRadiochemistryChemistryDNA glycosylaseSuperoxide dismutaseOxidative stressInhalationSmall intestineAntioxidantDismutaseCatalaseAntidepressantKidneyDeoxyguanosineAntioxidant capacityLipid peroxideOxidative stress markerLow dose rate? irradiationLow dose irradiationForced swimmingGlutathioneRadonRedoxOxidative phosphorylationMedicinePharmacology
5Publications
1H-index
1Citations
Publications 7
Newest
#1Takahiro Kataoka (RMIT: RMIT University)H-Index: 16
#2Norie Kanzaki (JAEA: Japan Atomic Energy Agency)H-Index: 5
Last. Fumihiro Mitsunobu (Okayama University)H-Index: 22
view all 11 authors...
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#1Takahiro Kataoka (RMIT: RMIT University)H-Index: 16
#2Hina Shuto (RMIT: RMIT University)H-Index: 1
Last. Hiroaki Terato (Okayama University)
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Radon inhalation decreases the level of lipid peroxide (LPO); this is attributed to the activation of antioxidative functions. This activation contributes to the beneficial effects of radon therapy, but there are no studies on the risks of radon therapy, such as DNA damage. We evaluated the effect of radon inhalation on DNA damage caused by oxidative stress and explored the underlying mechanisms. Mice were exposed to radon inhalation at concentrations of 2 or 20 kBq/m3 (for one, three, or 10 day...
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#1Tetsuya Nakada (RMIT: RMIT University)H-Index: 1
#2Takahiro Kataoka (RMIT: RMIT University)H-Index: 16
Last. Kiyonori Yamaoka (RMIT: RMIT University)H-Index: 28
view all 8 authors...
The forced swim test (FST) induces immobility in mice. Low-dose (high-dose-rate) X-irradiation inhibits FSTinduced immobility in mice due to its antioxidative function. We evaluated the effects of low-dose γ-irradiation at a low-dose-rate on the FST-induced depletion of antioxidants in mouse organs. Mice received whole-body low-dose-rate (0.6 or 3.0 mGy/h) of low-dose γ-irradiation for 1 week, followed by daily FSTs (5 days). The immobility rate on day 2 compared to day 1 was significantly lower...
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#1Shota NaoeH-Index: 1
#2Takahiro KataokaH-Index: 16
Last. Kiyonori YamaokaH-Index: 28
view all 10 authors...
Source
#1Takahiro KataokaH-Index: 16
#2Norie KanzakiH-Index: 5
Last. Kiyonori YamaokaH-Index: 28
view all 11 authors...
Source
#1Takahiro Kataoka (RMIT: RMIT University)H-Index: 16
#2Norie Kanzaki (JAEA: Japan Atomic Energy Agency)H-Index: 5
Last. Kiyonori Yamaoka (RMIT: RMIT University)H-Index: 28
view all 11 authors...
Radon inhalation activates antioxidative functions in mouse organs, thereby contributing to inhibition of oxidative stress-induced damage. However, the specific redox state of each organ after radon inhalation has not been reported. Therefore, in this study, we evaluated the redox state of various organs in mice following radon inhalation at concentrations of 2 or 20 kBq/m3 for 1, 3 or 10 days. Scatter plots were used to evaluate the relationship between antioxidative function and oxidative stre...
1 CitationsSource
#1Takahiro Kataoka (RMIT: RMIT University)H-Index: 16
#2Hina Shuto (RMIT: RMIT University)H-Index: 1
Last. Kiyonori Yamaoka (RMIT: RMIT University)H-Index: 28
view all 10 authors...
The forced swim test (FST) is a screening model for antidepressant activity; it causes immobility and induces oxidative stress. We previously reported that radon inhalation has antidepressant-like effects in mice potentially through the activation of antioxidative functions upon radon inhalation. This study aimed to investigate the effect of prior and post low-dose X-irradiation (0.1, 0.5, 1.0 and 2.0 Gy) on FST-induced immobility and oxidative stress in the mouse brain, and the differences, if ...
2 CitationsSource