Dan Yin
CytotoxicityGenetic enhancementDrug carrierNanoparticlePhotothermal therapyChemistryProgenitor cellIn vivoAlbuminChemotherapyCombination therapyBiocompatibilityDrug deliveryDrugProtein CoronaBiomoleculeCancer researchRadiation therapyCancer stem cellImmune system
3Publications
2H-index
2Citations
Publications 3
Newest
#1Hanmei LiH-Index: 2
#2Yao WangH-Index: 1
Last. Qiang Peng (Sichuan University)H-Index: 25
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Abstract In most cases, once nanoparticles (NPs) enter the blood, their surface is covered by biological molecules, especially proteins, forming a so-called protein corona (PC). As a result, what the cells of the body “see” is not the NPs as formulated by the chemists, but the PC. In this way, the PC can influence the effects of the NPs and even mask the desired effects of the NP components. While this can argue for trying to inhibit protein-nanomaterial interactions, encapsulating NPs in an end...
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#1Hanmei LiH-Index: 2
#2Dan YinH-Index: 2
Last. Qiang Peng (Sichuan University)H-Index: 25
view all 6 authors...
Abstract Polydopamine (PDA) has shown great potentials in biomedical fields due largely to its unique physicochemical properties, including high photothermal transfer efficiency, excellent drug binding capacity, versatile adhesion ability, sensitive pH responsibility and great biocompatibility and biodegradability. These properties confer PDA-based nanoparticles the potentials either as the drug carriers for advanced drug delivery or as the bioactive agents for photothermal therapy, imaging and ...
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#1Qi TangH-Index: 2
#2Dan YinH-Index: 2
Last. Hanmei LiH-Index: 2
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Cancer stem cells (CSCs) show self-renewal ability and multipotential differentiation like normal stem or progenitor cells, and which proliferate uncontrollably and can escape the effects of drugs and phagocytosis by immune cells. Traditional monotherapies such as surgical resection, radiotherapy and chemotherapy can't eradicate CSCs. Combination therapy may be more effective at eliminating CSCs. The present review summarizes the characteristics of CSCs and several promising combination therapie...
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