Giuseppe Vanella
Vita-Salute San Raffaele University
Internal medicineRadiologySurgeryPathologyOncologySingle-nucleotide polymorphismProspective cohort studyAsymptomaticColonoscopyEndoscopyDiseasePancreatic cancerEndoscopic ultrasoundPublication biasCystPancreatic ductal adenocarcinomaCoronavirus disease 2019 (COVID-19)In patientIncidence (epidemiology)Confidence intervalCancer researchGeneral surgeryMedicineGastroenterologyMeta-analysis
Publications 84
#1Laura Pistoni (UniPi: University of Pisa)H-Index: 1
#2Manuel Gentiluomo (UniPi: University of Pisa)H-Index: 6
Last. Yogesh K. Vashist (UHH: University of Hamburg)H-Index: 27
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Pancreatic ductal adenocarcinoma (PDAC) is among the most lethal cancers. Its poor prognosis is predominantly due to the fact that most patients remain asymptomatic until the disease reaches an advanced stage, alongside the lack of early markers and screening strategies. A better understanding of PDAC risk factors is essential for the identification of groups at high risk in the population. Genome-wide association studies (GWAS) have been a powerful tool for detecting genetic variants associated...
#1Giuseppe Vanella (UniSR: Vita-Salute San Raffaele University)H-Index: 8
#2Giuseppe Dell’Anna (UniSR: Vita-Salute San Raffaele University)
Last. Paolo Giorgio Arcidiacono (UniSR: Vita-Salute San Raffaele University)H-Index: 40
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#1Giuseppe VanellaH-Index: 8
Last. G. CapursoH-Index: 2
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#2Manuel Gentiluomo (UniPi: University of Pisa)H-Index: 6
Last. Daniele Campa (UniPi: University of Pisa)H-Index: 34
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Background Most cases of pancreatic ductal adenocarcinoma (PDAC) are asymptomatic in early stages, and the disease is typically diagnosed in advanced phases, resulting in very high mortality. Tools to identify individuals at high risk of developing PDAC would be useful to improve chances of early detection. Objective We generated a polygenic risk score (PRS) for PDAC risk prediction, combining the effect of known risk SNPs, and carried out an exploratory analysis of a multifactorial score. Metho...
5 CitationsSource
#1Gemma Rossi (UniSR: Vita-Salute San Raffaele University)H-Index: 5
#2Maria Chiara Petrone (UniSR: Vita-Salute San Raffaele University)H-Index: 19
Last. Paolo Giorgio Arcidiacono (UniSR: Vita-Salute San Raffaele University)H-Index: 40
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#2Livia Archibugi (UniSR: Vita-Salute San Raffaele University)H-Index: 13
Last. Enrique de-MadariaH-Index: 18
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OBJECTIVES post-endoscopic retrograde cholangiopancreatography (ERCP) acute pancreatitis (PEP) is a frequent complication of this endoscopic procedure. Chronic statin intake has been linked to lower incidence and severity of acute pancreatitis (AP). Periprocedural rectal administration of non-steroidal anti-inflammatory drugs is protective against PEP, but the role of chronic acetylsalicylic-acid (ASA) treatment is unclear. We aimed to investigate whether statins and chronic ASA intake are assoc...
1 CitationsSource
#1Giuseppe Vanella (UniSR: Vita-Salute San Raffaele University)H-Index: 8
#2Domenico TamburrinoH-Index: 16
Last. Paolo Giorgio Arcidiacono (UniSR: Vita-Salute San Raffaele University)H-Index: 40
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#1Michiel Bronswijk (Katholieke Universiteit Leuven)H-Index: 3
#2Giuseppe VanellaH-Index: 8
Last. Schalk Van der Merwe (Katholieke Universiteit Leuven)H-Index: 29
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BACKGROUND AND AIMS In the management of gastric outlet obstruction (GOO), EUS-guided gastroenterostomy (EUS-GE) seems safe and more effective than enteral stent placement. However, comparisons with laparoscopic gastroenterostomy (L-GE) are scarce. Our aim was to perform a propensity score-matched comparison between EUS-GE and L-GE. METHODS An international, multicenter, retrospective analysis was performed of consecutive EUS-GE and L-GE procedures in 3 academic centers (Jan 2015 to May 2020), u...
4 CitationsSource
#1Manuel Gentiluomo (UniPi: University of Pisa)H-Index: 6
#2C. Corradi (UniPi: University of Pisa)H-Index: 1
Last. Gabriele Capurso (UniSR: Vita-Salute San Raffaele University)H-Index: 56
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Although pancreatic ductal adenocarcinoma (PDAC) survival is poor, there are differences in patients' response to the treatments. Detection of predictive biomarkers explaining these differences is of the utmost importance. In a recent study two genetic markers (CD44-rs353630 and CHI3L2-rs684559) were reported to be associated with survival after PDAC resection. We attempted to replicate the associations in 1856 PDAC patients (685 resected with stage I/II) from the PANcreatic Disease ReseArch (PA...