Kuang Wei
Zunyi Medical College
H&E stainEndocrinologyHippocampal formationMolecular biologyTyrosine hydroxylaseRegeneration (biology)EnolaseMesenchymal stem cellNeuroprotectionWestern blotAxonGlial fibrillary acidic proteinIcariinNeuNHippocampusMorris water navigation taskFlow cytometryCell cultureBlotCell biology
3Publications
1H-index
10Citations
Publications 3
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#1Kuang Wei (Zunyi Medical College)H-Index: 1
#2Tao Liu (Zunyi Medical College)H-Index: 2
Last. Changyin Yu (Zunyi Medical College)H-Index: 3
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#1Kuang Wei (Zunyi Medical College)H-Index: 1
#2Tao Liu (Zunyi Medical College)H-Index: 2
Last. Changyin Yu (Zunyi Medical College)H-Index: 3
view all 6 authors...
The purpose of this study is to observe the effect of icariside II (ICS II) on the differentiation of human amniotic mesenchymal stem cells (hAMSCs) into dopaminergic neuron-like cells, the involvement of PI3K signaling pathway inhibitors. After identifying hAMSCs by flow cytometry, hAMSCs were induced and treated with ICS II at 10 μmol/L, 3 μmol/L, 1 μmol/L, and 0 μmol/L. hAMSCs in the LY294002+3μM ICS II group were pretreated with 20 μmol/L LY294002, a PI3K-specific inhibitor, for 1 h, and the...
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#1Tao Liu (Zunyi Medical College)H-Index: 2
#2Fang He (Zunyi Medical College)H-Index: 2
Last. Changyin Yu (Zunyi Medical College)H-Index: 3
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Chronic cerebral hypoperfusion (CCH) is a basic pathological process that is comorbid with brain diseases, such as vascular Parkinsonism and Alzheimer’s disease. Icariside II (ICS II), which is one of the main metabolites of icariin, has anti-inflammatory and antioxidant effects and protects against ischemic brain injury. This study aims to investigate the neuroprotective effects of ICS II on neuronal axon regeneration-related factors in a CCH rat model. Sprague-Dawley (SD) rats were divided int...
5 Citations