Simon Matoori
Paracelsus Private Medical University of Salzburg
RadiologyMagnetic resonance imagingUltrasoundEnzymeLiposomeChemistryRadiological weaponIn vivoPeritoneal dialysisNeuroradiologyHepatic encephalopathyHyperammonemiaEnzyme assayPopulationPolymersomeInterventional radiologyDomestic violenceMedicineUrea cyclePharmacology
Publications 27
#1Andreas Gutzeit (Paracelsus Private Medical University of Salzburg)H-Index: 17
#2Elisabeth Sartoretti (UZH: University of Zurich)H-Index: 1
Last. Thomas Sartoretti (UM: Maastricht University)H-Index: 1
view all 18 authors...
Objectives We investigate in what percentage of cases and to what extent radiological reports change when radiologists directly communicate with patients after imaging examinations. Methods One hundred twenty-two consecutive outpatients undergoing MRI examinations at a single center were prospectively included. Radiological reports of the patients were drafted by two radiologists in consensus using only the clinical information that was made available by the referring physicians. Thereafter, one...
#1Simon Matoori (Harvard University)H-Index: 9
#2Bharti Khurana (Brigham and Women's Hospital)H-Index: 18
Last. Andreas GutzeitH-Index: 17
view all 9 authors...
Faced with the COVID-19 pandemic, many countries both in Europe and across the world implemented strict stay-at-home orders. These measures helped to slow the spread of the coronavirus but also led to increased mental and physical health issues for the domestically confined population, including an increase in the occurrence of intimate partner violence (IPV) in many countries. IPV is defined as behavior that inflicts physical, psychological, or sexual harm within an intimate relationship. We be...
2 CitationsSource
#1Simon Matoori (Wyss Institute for Biologically Inspired Engineering)
#1Simon Matoori (Wyss Institute for Biologically Inspired Engineering)H-Index: 9
Last. David J. Mooney (Wyss Institute for Biologically Inspired Engineering)H-Index: 164
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Current treatment options for foot ulcers, a serious and prevalent complication of diabetes, remain nonspecific. In this Perspective, we present recent advances in understanding the pathophysiology of diabetic wound healing and the emergence of previously unidentified targets. We discuss wound dressings tailored to the diabetic wound environment currently under development.
#1Simon MatooriH-Index: 9
#2Vincent ForsterH-Index: 7
Last. Meriam KabbajH-Index: 2
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Abstract Liposomal supported peritoneal dialysis (LSPD) with transmembrane pH-gradient liposomes was previously shown to enhance ammonia removal in cirrhotic rats and holds promise for the treatment of hyperammonemic crises-associated disorders. The main objective of this work was to conduct the preclinical evaluation of LSPD in terms of pharmacokinetics, ammonia uptake, and toxicology to seek regulatory approval for a first-in-human study. The formulation containing citric acid-loaded liposomes...
1 CitationsSource
#1Simon Matoori (Harvard University)H-Index: 9
#2Bharti Khurana (Brigham and Women's Hospital)H-Index: 18
Last. Andreas Gutzeit (ETH Zurich)H-Index: 17
view all 8 authors...
• The COVID-19 crisis resulted in a variety of physical and mental health issues beyond the viral infection itself, as indicated by an increase in domestic violence. • Radiologists should be aware of typical intimate partner violence (IPV) injury patterns, actively ask potential IPV victims about the cause of injury, and be familiar with support systems for IPV victims of their institutions. • Emergency and radiology departments should review their protocols for identifying and supporting IPV vi...
13 CitationsSource
#1Simon Matoori (ETH Zurich)H-Index: 9
#2Jean-Christophe Leroux (ETH Zurich)H-Index: 82
Soon after the discovery of polymeric vesicles (polymersomes), reports of their high membrane stability raised hopes for the development of next generation vesicles for drug delivery and diagnostic applications. Twenty-five years later, however, liposomes remain the only clinically tested colloidal vesicular formulations. To highlight the translational challenges faced by polymersomes, we critically reviewed a selection of polymersome formulations with a focus on their pharmacokinetic and pharma...
14 CitationsSource
#1Simon Matoori (Harvard University)H-Index: 9
#2David J. Mooney (Harvard University)H-Index: 164
In emergency medicine, blood lactate levels are commonly measured to assess the severity and response to treatment of hypoperfusion-related diseases (e.g., sepsis, trauma, cardiac arrest). Clinical blood lactate testing is conducted with laboratory analyzers, leading to a delay of 3 h between triage and lactate result. Here, a fluorescence-based blood lactate assay, which can be utilized for bedside testing, based on measuring the hydrogen peroxide generated by the enzymatic oxidation of lactate...
#1Andreas Gutzeit (ETH Zurich)H-Index: 17
#2Qiubai Li (UTSW: University of Texas Southwestern Medical Center)H-Index: 2
Last. Liang Wang (HUST: Huazhong University of Science and Technology)H-Index: 12
view all 5 authors...
6 CitationsSource
#1Andreas GutzeitH-Index: 17
#2Arne FischmannH-Index: 1
Last. Matthias Meissnitzer (Paracelsus Private Medical University of Salzburg)H-Index: 12
view all 21 authors...
BACKGROUND: The aim of the study is to investigate how well patients remember the radiologist's name after a radiological examination, and whether giving the patient a business card improves the patient's perception of the radiologist's professionalism and esteem. METHODS: In this prospective and randomized two-centre study, a total of 141 patients with BI-RADS 1 and 2 scores were included. After screening examination comprising mammography and ultrasound by a radiologist, 71 patients received a...
4 CitationsSource
#1Simon Matoori (ETH Zurich)H-Index: 9
#2Yinyin Bao (ETH Zurich)H-Index: 16
Last. Jean-Christophe Leroux (ETH Zurich)H-Index: 82
view all 9 authors...
Ammonia-scavenging transmembrane pH-gradient poly(styrene)-b-poly(ethylene oxide) polymersomes are investigated for the oral treatment and diagnosis of hyperammonemia, a condition associated with serious neurologic complications in patients with liver disease as well as in infants with urea cycle disorders. While these polymersomes are highly stable in simulated intestinal fluids at extreme bile salt and osmolality conditions, they unexpectedly do not reduce plasmatic ammonia levels in cirrhotic...
10 CitationsSource