Asami Nishikori
RMIT University
Internal medicineSomatic hypermutationImmunoglobulin class switchingImmunoglobulin EPathologyAntigenAscusMolecular biologyMucocutaneous zoneAntibodyDermatologyNatural historyLymphatic systemCytologyImmunologyImmunohistochemistryPathologicalActivation-induced (cytidine) deaminaseCastleman diseaseLiquid-based cytologyPlasma cellHelicobacter pyloriAnasarcaChemotherapyInflammationCytidine deaminaseEosinophilHemosiderinNot Otherwise SpecifiedPeripheral T-cell lymphomaLeukemiaOrganomegalyLymph node biopsyMetastasisHydroxycarbamideLymphomaStomachMALT lymphomaLymphMast cellEosinophilicSerum ironContext (language use)Peripheral T-cell lymphoma not otherwise specifiedIgG4-related diseaseAdult T-cell leukemia/lymphomaLymph nodePathogenesisMethotrexateGastric mucosaEpstein-Barr Virus-Positive Mucocutaneous UlcerGene rearrangementHybrid captureScreening methodPolymerase chain reactionCancer researchHistopathologyHistologyPapanicolaou stainMedicineCohortPrimer (molecular biology)IL-2 receptorBiologyGastroenterologyGerminal center
Publications 7
#1Atsuko Nasu (RMIT: RMIT University)
#1Atsuko Nasu (RMIT: RMIT University)H-Index: 2
Last. Yasuharu Sato (RMIT: RMIT University)H-Index: 32
view all 9 authors...
Differentiation between adult T-cell leukemia/lymphoma (ATLL) and peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS), is often challenging based on pathological findings alone. Although serum anti-HTLV-1 antibody positivity is required for ATLL diagnosis, this information is often not available at the time of pathological diagnosis. Therefore, we examined whether the expression of SOX4 and p16 would be helpful for differentiating the two disease entities. We immunohistochemically exa...
Immunoglobulin G4-related disease (IgG4-RD) is a systemic disorder characterized by tissue fibrosis and intense lymphoplasmacytic infiltration, causing progressive organ dysfunction. Activation-induced cytidine deaminase (AID), a deaminase normally expressed in activated B-cells in germinal centers, edits ribonucleotides to induce somatic hypermutation and class switching of immunoglobulin. While AID expression is strictly controlled under physiological conditions, chronic inflammation has been ...
#1Yusuke SaikiH-Index: 1
#2Yuka GionH-Index: 13
Last. Yasuharu SatoH-Index: 32
view all 5 authors...
Objective: Human papillomaviruses (HPVs) are DNA viruses, of which over 120 types have been identified. The main screening methods for HPV-DNA include the hybrid capture II (HC-II) and polymerase chain reaction (PCR) assays. Liquid-based cytology (LBC) is a high-quality technique developed to improve the diagnostic reliability of traditional Papanicolaou tests (Pap tests). However, relatively few studies have compared the efficacy of PCR and HC-II assays using cervicovaginal LBC specimens. In th...
#1Tomoka Ikeda (Okayama University)H-Index: 2
#2Yuka Gion (RMIT: RMIT University)H-Index: 13
Last. Yasuharu Sato (RMIT: RMIT University)H-Index: 32
view all 8 authors...
Epstein-Barr virus (EBV)-positive mucocutaneous ulcer (EBVMCU) is a unifocal mucosal or cutaneous ulcer that is histologically characterized by proliferating EBV-positive atypical B cells. While EBVMCU demonstrates a histology similar to that of EBV-positive diffuse large B-cell lymphoma (DLBCL), their clinical behavior differs. Thus, characterizing distinguishing features of EBVMCU and EBV-positive DLBCL is critical. To identify unique characteristics between EBVMCU and lymphoma, we analyzed th...
4 CitationsSource
#1Yanyan Han (Okayama University)H-Index: 1
#2Takuro Igawa (Okayama University)H-Index: 5
Last. Yasuharu Sato (RMIT: RMIT University)H-Index: 32
view all 7 authors...
Plasma cell-type Castleman disease (PCD) is a rare idiopathic atypical lymphoproliferative disorder. It is difficult to differentiate between PCD and IgG4-related disease (IgG4-RD) based on histology alone. As PCD often presents with abundant hemosiderin deposition, lymph node lesions obtained from 22 PCD patients and 12 IgG4-RD patients were analyzed using Prussian blue staining to clarify whether hemosiderin deposition is effective in distinguishing between these two diseases. The analysis dis...
2 CitationsSource
#1Yuka Gion (RMIT: RMIT University)H-Index: 13
#2Mitsuhiro Okano (International University of Health and Welfare)H-Index: 29
Last. Yasuharu Sato (RMIT: RMIT University)H-Index: 32
view all 11 authors...
Cross-linking of antigen-specific IgE bound to the high-affinity IgE receptor (FceRI) on the surface of mast cells with multivalent antigens results in the release of mediators and development of type 2 inflammation. FceRI expression and IgE synthesis are, therefore, critical for type 2 inflammatory disease development. In an attempt to clarify the relationship between eosinophilic chronic rhinosinusitis (ECRS) and mast cell infiltration, we analyzed mast cell infiltration at lesion sites and de...
2 CitationsSource
#1Rika Omote (Okayama University)H-Index: 3
#2Yuka Gion (Okayama University)H-Index: 13
Last. Yasuharu Sato (Okayama University)H-Index: 32
view all 8 authors...
Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT) lymphoma of the stomach is mainly associated with Helicobacter pylori infection, and H. pylori eradication therapy is often effective. However, 20–30% of the cases of MALT lymphoma are resistant to the eradication therapy, and translocation of the API2-MALT1 gene is often found in these cases. Most cases without translocation of API2-MALT1 are localized to the stomach, whereas some cases with this translocation are a m...
1 CitationsSource