Anthony Yip
University of California, San Diego
Internal medicineRadiologyOncologyLogistic regressionNeurocognitiveEsophagusBrain tumorDiseaseEsophageal cancerNivolumabAtrophyWhite matterIpilimumabNuclear medicineIn patientCost effectivenessOverall survivalPerioperativeRadiation therapyMedicineCohortFractional anisotropy
16Publications
2H-index
8Citations
Publications 18
Newest
#1Mia A Salans (UCSD: University of California, San Diego)H-Index: 3
#2Patrick T Courtney (UCSD: University of California, San Diego)H-Index: 2
Last. James D. Murphy (UCSD: University of California, San Diego)H-Index: 37
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BACKGROUND Adjuvant ipilimumab was found to improve the overall survival and reduce toxicity compared to high-dose interferon (HDI) in patients with resected, high-risk melanoma. However, the cost of ipilimumab is substantially higher than HDI. This study evaluates the cost-effectiveness of ipilimumab as an adjuvant treatment in melanoma from a healthcare perspective. METHODS We designed a Markov model simulating resected, high-risk melanoma patients receiving either ipilimumab or HDI. Transitio...
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#1Mia Salans (ISMMS: Icahn School of Medicine at Mount Sinai)
#2Anthony YipH-Index: 2
Last. Yoseph Dalia (UT: University of Tennessee)
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Objective null We conducted a prospective clinical trial of patients receiving radiation (RT) for brain metastases to identify clinical predictors of pre-RT and post-RT health-related quality of life (hrQoL). null Materials and methods null Patients with brain metastases completed overall (European Organisation for Research and Treatment of Cancer QLQ C15-PAL) and brain tumor-specific (QLQ-BN20) hrQoL assessments pre-RT (n=127) and 1 (n=56) and 3 (n=45) months post-RT. Linear and proportional-od...
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#1Mia A Salans (UCSD: University of California, San Diego)H-Index: 3
#2Michelle D. Tibbs (UCSD: University of California, San Diego)H-Index: 4
Last. Jona A. Hattangadi-Gluth (UCSD: University of California, San Diego)H-Index: 23
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BACKGROUND We explored fine motor skills (FMS) before and after brain radiotherapy (RT), analyzing associations between longitudinal FMS and imaging biomarkers of cortical and white matter (WM) integrity in motor regions of interest (ROIs). METHODS On a prospective trial, 52 primary brain tumor patients receiving fractionated brain RT underwent volumetric brain MRI, diffusion tensor imaging, and FMS assessments (Delis-Kaplan Executive Function System Trail Making Test Motor Speed [DKEFS-MS], Gro...
2 CitationsSource
#1Mia A Salans (UCSD: University of California, San Diego)H-Index: 3
#2Michelle D. Tibbs (UCSD: University of California, San Diego)H-Index: 4
Last. Tonya M. Pan-Weisz (UCSD: University of California, San Diego)H-Index: 3
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ABSTRACT null null Background null We conducted the first prospective longitudinal study examining the independent association between patient-reported hrQoL (physical, social/family, emotional, functional, and brain cancer-specific) and neurocognitive function (NCF), while controlling for mood symptoms in primary brain tumor patients. null null null Methods null Primary brain tumor patients (n=59) receiving brain radiotherapy (RT) underwent hrQOL (Functional Assessment of Cancer Therapy-Brain),...
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#1P Travis Courtney (UCSD: University of California, San Diego)H-Index: 1
#2Anthony Yip (UCSD: University of California, San Diego)H-Index: 2
Last. James D. Murphy (UCSD: University of California, San Diego)H-Index: 37
view all 6 authors...
Importance Treatment with nivolumab-ipilimumab combination therapy was found to improve overall survival compared with chemotherapy among patients with advanced non–small cell lung cancer (NSCLC) in the CheckMate 227 clinical trial. However, these drugs are substantially more expensive than chemotherapy and, given the high incidence of advanced NSCLC, the incorporation of dual immune checkpoint inhibitors into the standard of care could have substantial economic consequences. Objective To assess...
1 CitationsSource
#1Reith Sarkar (UCSD: University of California, San Diego)H-Index: 7
Last. James D. MurphyH-Index: 37
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Objectives Preoperative radiotherapy improves outcomes for operable esophageal cancer patients, though the proximity of the heart to the esophagus puts patients at risk of radiation-induced cardiovascular disease. This study characterizes the impact of radiotherapy and different radiation techniques on cardiovascular morbidity among a cohort of esophageal cancer patients. Materials and methods We identified 1125 patients aged 65 and older diagnosed between 2000 and 2011 with esophageal cancer wh...
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#4Mia A Salans (UCSD: University of California, San Diego)H-Index: 3
#5Kathryn R. Tringale (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 11
Abstract Background The corpus callosum (CC) and intra-hemispheric white matter tracts (IHWM) subserve critical aspects of attention and processing speed. We analyzed imaging biomarkers of microstructural injury within these regions and association with attention/processing speed decline post-radiotherapy in primary brain tumor patients. Methods On a prospective clinical trial, 44 primary brain tumor patients underwent cognitive testing and MRI/diffusion-weighted imaging pre-radiotherapy, and 3-...
5 CitationsSource
#1Anthony YipH-Index: 2
Last. Jona A. Hattangadi-GluthH-Index: 23
view all 3 authors...
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#1Michelle D. Tibbs (UCSD: University of California, San Diego)H-Index: 4
#2Minh-Phuong Huynh-Le (UCSD: University of California, San Diego)H-Index: 10
Last. Jona A. Hattangadi-Gluth (UCSD: University of California, San Diego)H-Index: 23
view all 12 authors...
ABSTRACT Purpose To investigate the association between imaging biomarkers of radiation-induced white matter (WM) injury within perisylvian regions and longitudinal language decline in brain tumor patients. Methods and Materials Primary brain tumor patients (n=44) on a prospective trial underwent brain MRI, diffusion-weighted imaging, and language assessments of naming [Boston Naming Test (BNT)] and fluency [DKEFS-Category Fluency (DKEFS-CF)] at baseline, 3, 6, and 12-months post-fractionated ra...
5 CitationsSource
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