Marco Bassetto
Genetic enhancementGene silencingHigh-content screeningMagnetofectionNanotechnologyChemistryMaterials scienceSmall interfering RNAEx vivoRetinaDrug deliveryRetinalRetinal degenerationRetinitis pigmentosaRetinal DisorderRNAMedicineMagnetic nanoparticlesCell biology
3Publications
1H-index
2Citations
Publications 3
Newest
#1Marco BassettoH-Index: 1
#2Merve Sen (University of Tübingen)H-Index: 2
Last. Olivier ZelphatiH-Index: 14
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The prevalence of retinal disorders associated with visual impairment and blindness is increasing worldwide, while most of them remain without effective treatment. Pharmacological and molecular therapy development is hampered by the lack of effective drug delivery into the posterior segment of the eye. Among molecular approaches, RNA-interference (RNAi) features strong advantages, yet delivering it to the inner layer of the retina appears extremely challenging. To address this, we developed an o...
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#1Merve Sen (University of Tübingen)H-Index: 2
#2Marco BassettoH-Index: 1
Last. Blanca Arango-Gonzalez (University of Tübingen)H-Index: 18
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The use of synthetic RNA for research purposes as well as RNA-based therapy and vaccination has gained increasing importance. Given the anatomical seclusion of the eye, small interfering RNA (siRNA)-induced gene silencing bears great potential for targeted reduction of pathological gene expression that may allow rational treatment of chronic eye diseases in the future. However, there is yet an unmet need for techniques providing safe and efficient siRNA delivery to the retina. We used magnetic n...
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#1Marco BassettoH-Index: 1
#2Daniel Roberto Ajoy Moreno (UDS: University of Strasbourg)
Last. Olivier ZelphatiH-Index: 14
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