Yaling Hu
Nanjing Medical University
GeneNeuritePhosphorylationInternal medicineEndocrinologyNeuroscienceChemistryMicroarrayApoptosisProtein kinase CGlioblastomaWestern blotACADMInfiltration (medical)Dendritic cellEnosHypoxia (medical)Corticospinal tractSpinal cordL-GlucoseTraumatic brain injuryClear cell renal cell carcinomaMitotic cytokinesisACADM GeneMitotic chromosome condensationShort survivalCancer researchGene isoformFlow cytometryCarcinogenesisSignal transductionComputational biologyMedicineProtein kinase BMicroarray analysis techniquesBiologyGap-43 protein
Publications 5
#1Yaling Hu (Nanjing Medical University)H-Index: 1
#2Yingdi Jiang (Nanjing Medical University)H-Index: 1
Last. Ying Yin (Nanjing Medical University)H-Index: 8
view all 11 authors...
Previous studies have demonstrated that glucocorticoid receptor β (GRβ) functions as an oncoprotein, regulating the malignant phenotypes and stem-like cell maintaining in human glioblastoma (GBM). Of the glucocorticoid receptor (GR) isoforms, GRβ and GRα are highly homologous, though the mechanism underlying the distinct functions of these two isoforms in GBM has not been clarified. Here by establishing a carboxyl-terminal (COOH-terminal) deletion mutant, we determined that GRβ can be ubiquitina...
#2Bo ZhangH-Index: 36
Last. Zou J
view all 8 authors...
#1Hai-Ping Zhang (Nanjing Medical University)H-Index: 2
#2Jian Zou (Nanjing Medical University)H-Index: 20
Last. Hui-Jun Mu (Nanjing Medical University)H-Index: 9
view all 7 authors...
Clear cell renal cell carcinoma (ccRCC) is one of the most common and lethal types of cancer within the urinary system. Great efforts have been made to elucidate the pathogeny. However, the molecular mechanism of ccRCC is still not well understood. The aim of this study is to identify key genes in the carcinogenesis and progression of ccRCC. The mRNA microarray dataset GSE53757 was downloaded from the Gene Expression Omnibus database. The GSE53757 dataset contains tumor and matched paracancerous...
#1Bo Zhang (Nanjing Medical University)H-Index: 36
#2Zaiwang Li (Southern University of Science and Technology)H-Index: 11
Last. Jian Zou (Nanjing Medical University)H-Index: 20
view all 15 authors...
Traumatic brain injury (TBI) is a common cause of death and disability. Enhancing the midline-crossing of the contralateral corticospinal tract (CST) to the denervated side of spinal cord facilitates functional recovery after TBI. Activation of the gamma isoform of PKC (PKCγ) in contralateral CST implicates its roles in promoting CST remodeling after TBI. In this study, we deployed loss and gain of function strategies in N2a cells and primary cortical neurons in vitro, and demonstrated that PKCγ...
#1Xiaowen Yin (Nanjing Medical University)H-Index: 2
#2Jun ShaoH-Index: 9
Last. Yan Liu
view all 11 authors...
Objective To explore repressive effects of transthyretitin (TTR) on the growth of human retinal endothelial cells (hREC) under high glucose and hypoxia environment. Methods hRECs were divided into 8 groups, including normal glucose group (5.5 mmol/L glucose), hypoxia group, high glucose group (25.0 mmol/L glucose), high glucose and hypoxia group, normal glucose group+TTR, normal glucose and hypoxia group+TTR, high glucose group+TTR, high glucose and hypoxia group+TTR. Flow cytometry was used to ...
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