Marina Deuker
Goethe University Frankfurt
EpidemiologyInternal medicineUrologyOncologyLogistic regressionStage (cooking)Hazard ratioCystectomyChemotherapyRenal cell carcinomaProstatectomyUrinary bladderProstate cancerNephrectomyBladder cancerKidney cancerAdenocarcinomaIn patientProportional hazards modelMedicineCohortCumulative incidence
72Publications
7H-index
107Citations
Publications 72
Newest
#1M. Wenzel (UdeM: Université de Montréal)H-Index: 8
#2Marina Deuker (UdeM: Université de Montréal)H-Index: 7
Last. Derya Tilki (UHH: University of Hamburg)H-Index: 60
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Abstract null null Background null The efficacy of tyrosine kinase inhibitor (TKI)-based therapy after previous immuno-oncology therapy (IO) failure has been addressed before. However, summary efficacy estimates have never been generated in these reports. We addressed this void. null null null Material and methods null We systematically examined TKI efficacy after IO-failure and generated weighted median progression-free survival (PFS) estimates for Pazopanib, Axitinib, Cabozantinib, Sunitinib. ...
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#1Lara Franziska Stolzenbach (UdeM: Université de Montréal)H-Index: 5
#2Marina Deuker (UdeM: Université de Montréal)H-Index: 7
Last. Pierre I. Karakiewicz (UdeM: Université de Montréal)H-Index: 7
view all 13 authors...
BACKGROUND We hypothesized that the residency status (rural area [RA] vs urban clusters [UC] vs urban areas [UA]) affects stage and cancer-specific mortality (CSM) in contemporary newly diagnosed prostate cancer (PCa) patients of all stages, regardless of treatment. METHODS Newly diagnosed PCa patients with available residency status were abstracted from the Surveillance, Epidemiology, and End Results database (2004-2016). Propensity-score (PS) matching, cumulative incidence plots, multivariate ...
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#1Noriyoshi Miura (Medical University of Vienna)H-Index: 5
#2Keiichiro Mori (Medical University of Vienna)H-Index: 10
Last. Shahrokh F. Shariat (Medical University of Vienna)H-Index: 136
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OBJECTIVE To assess the value of preoperative albumin to globulin ratio for predicting pathologic and oncological outcomes in patients with upper tract urothelial carcinoma treated with radical nephroureterectomy in a large multi-institutional cohort. MATERIALS AND METHODS Preoperative albumin to globulin ratio was assessed in a multi-institutional cohort of 2492 patients. Logistic regression analyses were performed to assess the association of the albumin to globulin ratio with pathologic featu...
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#1Victor M. Schuettfort (UHH: University of Hamburg)H-Index: 5
#2Kilian M. Gust (Medical University of Vienna)H-Index: 20
Last. Pierre I. Karakiewicz (UdeM: Université de Montréal)H-Index: 119
view all 21 authors...
BACKGROUND To investigate the predictive and prognostic value of the preoperative modified Glasgow Prognostic Score (mGPS) in patients with urothelial carcinoma of the bladder (UCB) treated with radical cystectomy (RC). METHODS We conducted a retrospective analysis of an established multicenter database consisting of 4,335 patients who were treated with RC +/- adjuvant chemotherapy for UCB between 1979 and 2012. The mGPS of each patient was calculated on the basis of preoperative serum C-reactiv...
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#1M. Wenzel (UdeM: Université de Montréal)H-Index: 8
#2Marina Deuker (UdeM: Université de Montréal)H-Index: 7
Last. Pierre I. Karakiewicz (UdeM: Université de Montréal)H-Index: 119
view all 12 authors...
Abstract Objective To test the effect of race/ethnicity on histological subtype, stage at presentation, and cancer specific mortality (CSM) in urethral cancer patients. Material and Methods Stratified analyses (Surveillance, Epidemiology and End Results [2004–2016]) tested the effect of race/ethnicity on histology and stage. Cumulative incidence-plots and multivariable competing-risks regression models (CRR), addressed CSM, after matching for TNM-stage, histology, age, and gender. Results Of 1,9...
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#1Stefano Luzzago (IEO: European Institute of Oncology)H-Index: 12
#2Carlotta Palumbo (UdeM: Université de Montréal)H-Index: 10
Last. Pierre I. Karakiewicz (UdeM: Université de Montréal)H-Index: 119
view all 15 authors...
Abstract Objectives Metabolic syndrome (MetS) and its components (high blood pressure, BMI ≥ 30, altered fasting glucose, low HDL cholesterol and high triglycerides) may undermine early perioperative outcomes after radical prostatectomy (RP). We tested this hypothesis. Materials & methods Within the National Inpatient Sample database (2008–2015) we identified RP patients. The effect of MetS was tested in four separate univariable analyses, as well as in multivariable regression models predicting...
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#1Giuseppe Rosiello (UdeM: Université de Montréal)H-Index: 8
#2Carlotta Palumbo (UdeM: Université de Montréal)H-Index: 10
Last. Pierre I. Karakiewicz (UdeM: Université de Montréal)H-Index: 119
view all 14 authors...
OBJECTIVE Our objective was to investigate age- and sex-related differences in the distribution of metastases in patients with metastatic bladder cancer. METHODS Within the National Inpatient Sample database (2008-2015), we identified 7040 patients with metastatic bladder cancer. Trend test and Chi-square test analyses were used to evaluate the relationship between age and site of metastases, according to sex. RESULTS Of 7040 patients with metastatic bladder cancer, 5226 (74.2%) were men and 181...
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#2Marina Deuker (UdeM: Université de Montréal)H-Index: 7
Last. Pierre I. Karakiewicz (UdeM: Université de Montréal)H-Index: 119
view all 13 authors...
OBJECTIVE To test whether radical prostatectomy might result in better survival than external beam radiation therapy in metastatic prostate cancer patients. METHODS Newly diagnosed metastatic prostate cancer patients with M1a/b substages, treated with radical prostatectomy or external beam radiation therapy were abstracted from the Surveillance, Epidemiology and End Results database (2004-2016). Temporal trend analyses, propensity score matching, cumulative incidence plots, multivariate competin...
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Background Intermediate risk prostate cancer (IR PCa) may exhibit a wide array of phenotypes, from favorable to unfavorable. NCCN criteria help distinguishing between favorable versus unfavorable subgroups. We studied and attempted to improve this classification. Methods Within the SEER database 2010-2016, we identified 19,193 IR PCa patients treated with radical prostatectomy. A multivariable logistic regression model predicting unfavorable IR PCa was developed and externally validated, in addi...
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#1Giuseppe Rosiello (UdeM: Université de Montréal)H-Index: 8
#2Carlotta Palumbo (UdeM: Université de Montréal)H-Index: 10
Last. Pierre I. Karakiewicz (UdeM: Université de Montréal)H-Index: 119
view all 14 authors...
Abstract Background To compare the effect of robot-assisted (RAPN) vs. open (OPN) partial nephrectomy on short-term postoperative outcomes and total hospital charges in frail patients with non-metastatic renal cell carcinoma (RCC). Methods Within the National Inpatient Sample database we identified 2745 RCC patients treated with either RAPN or OPN between 2008 and 2015, who met the Johns Hopkins Adjusted Clinical Groups frailty-defining indicator criteria. We examined the rates of RAPN vs. OPN o...
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