Austin J. Sim
CancerInternal medicineRadiologyOncologyMedical physicsSpecialtyMultidisciplinary approachT cellRenal cell carcinomaImmunotherapyStereotactic radiation therapySarcomaLymphomaMEDLINENivolumabProstate cancerRadiosurgeryNuclear medicineStereotactic radiotherapyRadiation oncologyStereotactic body radiotherapyMri guidedCar t cellsChimeric antigen receptorPublic relationsCancer researchMedical educationRadiation therapyFamily medicineMedicine
27Publications
6H-index
47Citations
Publications 35
Newest
#1Austin J. SimH-Index: 6
#2P.A. Shetty (USF: University of South Florida)
Last. George Daniel GrassH-Index: 5
view all 9 authors...
PURPOSE/OBJECTIVE(S) Melanoma is a more radioresistant and immunogenic histology, associated with a higher mutational burden. However, the influence of metastasis tissue location is unknown. We hypothesize exploiting these differences may allow therapy personalization. MATERIALS/METHODS We identified metastatic melanoma samples across 6 tissues (brain, liver, lung, lymph node [LN], skin, soft tissue [ST]), which were profiled for gene expression by microarray chips. Intrinsic radiosensitivity wa...
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#1P.A. Shetty (USF: University of South Florida)
#2Austin J. SimH-Index: 6
Last. K.A. AhmedH-Index: 2
view all 9 authors...
Purpose/Objective(s) null The soft tissues are a poorly studied subsite for metastases with unclear treatment paradigms. We hypothesize elucidating differences in these metastases by primary histology may allow for optimization of therapies. null null null Materials/Methods null We isolated soft tissue metastases with microarray data. A subset also had data from a 1,327-gene targeted exome sequencing assay. An existing radiosensitivity index (RSI) was used to estimate intrinsic radiosensitivity,...
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Purpose/objective(s) null The majority of patients with relapsed or refractory large B-cell lymphomas (R/R LBCL) treated with CAR-T cell therapy experience disease progression. We previously identified that most relapses include local failures at PET avid sites that were present prior to CAR T cell infusion. We hypothesize that targeting unfavorable lesions with bridging radiation (RT) may prevent local failure. null Materials/methods null We retrospectively identified R/R LBCL patients treated ...
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#2Idalid Franco (Harvard University)H-Index: 10
Last. Gita Suneja (HCI: Huntsman Cancer Institute)H-Index: 23
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PURPOSE/OBJECTIVE(S) To investigate radiation oncology (RO) program directors' (PDs) attitudes and practices regarding racial and ethnic diversity, equity and inclusion (DEI) and to better understand their potential impact on underrepresented in medicine (UIM) residents in RO. MATERIALS/METHODS A 28-item IRB-approved survey was developed using the validated Ethnic Harassment Experiences Scale and the Daily Life Experiences subscale, as well as input from DEI leaders in RO. Apart from demographic...
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The implementation of the radiation oncology alternative payment model (RO-APM) has raised concerns regarding the development of MRI-guided adaptive radiotherapy (MRgART). We sought to compare technical fee reimbursement under Fee-For-Service (FFS) to the proposed RO-APM for a typical MRI-Linac (MRL) patient load and distribution of 200 patients. In an exploratory aim, a modifier was added to the RO-APM (mRO-APM) to account for the resources necessary to provide this care. Traditional Medicare F...
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