Mitsugu Sekimoto
Kansai Medical University
DissectionCancerInternal medicineRadiologySurgeryOncologyImmunohistochemistryLaparoscopic surgeryChemotherapyPaclitaxelHepatocellular carcinomaPancreatectomyTriple-negative breast cancerSurgical oncologyPancreatic cancerGemcitabineLymph nodePancreatic ductal adenocarcinomaBorderline resectableColorectal cancerBreast cancerMedicineGastroenterology
65Publications
4H-index
53Citations
Publications 82
Newest
#1Hisashi Kosaka (Kansai Medical University)H-Index: 9
#2Masaki Kaibori (Kansai Medical University)H-Index: 33
Last. Mitsugu Sekimoto (Kansai Medical University)H-Index: 4
view all 5 authors...
BACKGROUND Postoperative adhesions are a potentially life-threatening complication of abdominal surgery. We previously showed that substance P (SP), acting through the neurokinin-1 receptor (NK-1R), is an important early mediator of adhesiogenesis through its regulation of the tissue plasminogen activator/plasminogen activator inhibitor-1 (PAI-1) fibrinolytic system. SP also mediates neurogenic inflammation by recruiting inflammatory leukocytes, such as neutrophils and macrophages. Our objective...
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#1Masaki Kaibori (Kansai Medical University)H-Index: 33
#2Hideyuki Matsushima (Kansai Medical University)H-Index: 6
Last. Mitsugu Sekimoto (Kansai Medical University)H-Index: 4
view all 7 authors...
Various tubes may be fixed to the skin by ligation using silk sutures after gastrointestinal surgery. We investigated the effects of a skin substitute, “Nonaht®,” on pain and skin inflammation at the fixation sites of various tubes. The effects of tubes (abdominal drains, small intestinal feeding tubes, and bile duct drainage tubes) fixed in place using either silk sutures or Nonaht were compared for 1–3 months. The median pain scores at the fixation site when abdominal drains were removed were ...
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#1Shigeru YamadaH-Index: 32
#2Hirotoshi TakiyamaH-Index: 6
Last. Hisahiro Matsubara (Chiba University)H-Index: 59
view all 13 authors...
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#1Shigeru YamadaH-Index: 32
#2Hirotoshi TakiyamaH-Index: 6
Last. Hisahiro Matsubara (Chiba University)H-Index: 59
view all 13 authors...
Background null This study aimed to assess the safety and efficacy of carbon-ion radiotherapy (CIRT) for salvage of previously X-ray-irradiated (XRT) locally recurrent rectal cancer (LRRC). null Methods null Between September 2005 and December 2017, 77 patients with LRRC were treated with CIRT re-irradiation. All the patients had received prior XRT with a median dose of 50.0 Gy (range 20-74 Gy), principally for neoadjuvant or adjuvant recurrence prophylaxis in 34 patients and for recurrence in 4...
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#1Katsuji TokuharaH-Index: 13
#2Terufumi YoshidaH-Index: 1
Last. Mitsugu Sekimoto (Kansai Medical University)H-Index: 4
view all 5 authors...
We investigated the efficacy and short-term outcomes of laparoscopy-assisted right hemicolectomy using the bottom-to-up approach (LBU-rHC) in right-side colon cancer (rCC) patients. We reviewed 114 patients with rCC underwent LBU-rHC between 2015 and 2019. LBU-rHC Surgical Procedures was shown below. After mobilizing the small intestine to the upper right abdomen, we cut the transition part between the intestinal mesenteric membrane and retroperitoneum near the third part of duodenum (DU). The s...
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#1Hisashi Kosaka (Kansai Medical University)H-Index: 9
#2Sohei Satoi (Anschutz Medical Campus)H-Index: 1
Last. Mitsugu Sekimoto (Kansai Medical University)H-Index: 4
view all 9 authors...
BACKGROUND Pancreatoduodenectomy (PD) is a technically complex procedure. Preoperative anticipation of the degree of difficulty could contribute to patient safety during trainee surgical education. METHODS We prospectively administered a questionnaire to the chief surgeon after each PD performed between 2016 and 2018 at our institution (99 consecutive patients). The surgeon rated the difficulty of the procedure; we then analyzed this information against perioperative data. RESULTS The difficulty...
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#1Tatsuma Sakaguchi (Kansai Medical University)H-Index: 10
#2Masaya Kotsuka (Kansai Medical University)H-Index: 7
Last. Mitsugu Sekimoto (Kansai Medical University)H-Index: 4
view all 4 authors...
INTRODUCTION Pneumoperitoneum usually requires emergency surgery. Asymptomatic idiopathic pneumoperitoneum is a rare subgroup of pneumoperitoneum for which a management algorithm has not been established. PRESENTATION OF CASE In an 88-year-old female patient, pneumoperitoneum was found incidentally by chest computed tomography during a periodic follow-up for sarcoidosis. Emergency admission was ordered for conservative treatment. Upper gastrointestinal endoscopy revealed edematous mucosa in the ...
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#1Katsuhiro Yoshikawa (Kansai Medical University)H-Index: 3
#2Mitsuaki Ishida (Kansai Medical University)H-Index: 6
Last. Tomoharu Sugie (Kansai Medical University)H-Index: 9
view all 6 authors...
BACKGROUND Triple-negative breast cancer (TNBC) is the most aggressive type of breast cancer. A recent study demonstrated the efficacy of anti-PD-L1 (anti-programmed death ligand-1) immunotherapy in patients with TNBC. However, the identification of TNBC patients who may benefit from immunotherapy is a critical issue. Several assays have been used to evaluate PD-L1 expression, and a few studies comparing PD-L1 expression using various primary antibodies in TNBC tissues have been reported. Howeve...
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#1Morihiko Ishizaki (Kansai Medical University)H-Index: 21
#2Masaki Kaibori (Kansai Medical University)H-Index: 33
Last. Mitsugu Sekimoto (Kansai Medical University)H-Index: 4
view all 6 authors...
A 36-year-old man had been diagnosed with a solitary hepatocellular carcinoma in the right lobe of the liver by computed tomography, and right hemihepatectomy was performed 16 years previously. Approximately 13 years later, he underwent partial hepatectomy because of intrahepatic recurrence in segment 4. Multinodular intrahepatic recurrences in the remnant liver were identified 19 months after repeat hepatectomy, and he underwent transcatheter arterial chemoembolization therapy. Ultimately, six ...
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#1Masaki Kaibori (Kansai Medical University)H-Index: 33
#2Hideyuki Matsushima (Kansai Medical University)H-Index: 6
Last. Kengo Yoshii (Kyoto Prefectural University of Medicine)H-Index: 10
view all 11 authors...
The aim of the current study was to investigate the efficacy and safety of sorafenib and intermittent hepatic arterial infusion chemotherapy with cisplatin for unresectable hepatocellular carcinoma (HCC) with severe portal vein invasion. The antitumor effect was a complete response in 1 of 38 patients, a partial response in 12 patients, stable disease in 16 patients, and progressive disease in 9 patients, for a 34.2% response rate and a 76.3% disease control rate. This regimen had favorable effi...
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