Jakub Sławski
University of Wrocław
EndosomeEnergy transferProtein–protein interactionElectron transferQuantum dotCytoskeletonHelixCell signalingNanoparticleBeta sheetBiosensorNanotechnologyChemistryMaterials sciencePorphyrinCover (algebra)Photoinduced electron transferNucleocytoplasmic TransportCytochrome cA proteinMoleculeSecretionRedoxFibroblast growth factorPhotochemistryIntracellularCrystallographyQuenchingFluorescenceCell biologyFörster resonance energy transfer
Publications 4
#1Jakub Sławski (UWr: University of Wrocław)H-Index: 3
#2Rafał Białek (Adam Mickiewicz University in Poznań)H-Index: 5
Last. Joanna Grzyb (UWr: University of Wrocław)H-Index: 14
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Colloidal quantum dots (QDs) are nanoparticles that are able to photoreduce redox proteins by electron transfer (ET). QDs are also able to transfer energy by resonance energy transfer (RET). Here, we address the question of the competition between these two routes of QDs' excitation quenching, using cadmium telluride QDs and cytochrome c (CytC) or its metal-substituted derivatives. We used both oxidized and reduced versions of native CytC, as well as fluorescent, nonreducible Zn(II)CytC, Sn(II)C...
#1Katarzyna Dominika Sluzalska (UWr: University of Wrocław)H-Index: 1
#2Jakub Sławski (UWr: University of Wrocław)H-Index: 3
Last. Malgorzata Zakrzewska (UWr: University of Wrocław)H-Index: 17
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Abstract Fibroblast growth factors 1 and2 (FGF1 and FGF2) are mainly considered as ligands of surface receptors through which they regulate a broad spectrum of biological processes. They are secreted in non-canonical way and, unlike other growth factors, they are able to translocate from the endosome to the cell interior. These unique features, as well as the role of the intracellular pool of FGF1 and FGF2, are far from being fully understood. An increasing number of reports address this problem...
2 CitationsSource
#1Jakub Sławski (UWr: University of Wrocław)H-Index: 3
#2Joanna Grzyb (UWr: University of Wrocław)H-Index: 3
Last. Joanna Grzyb (UWr: University of Wrocław)H-Index: 14
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The bionanohybrids are the junctions of at least two objects of different origin: abiotic and biotic. The abiotic part is a nanoparticle (often a fluorescent quantum dot), the biotical one may be a protein (especially fluorescent one or redox-active one), nucleic acid, carbohydrate as well as a simple organic molecule. When such a junction undergoes illumination, the energy transfer between the partners is possible. The nanoparticles, depending on their characteristics, may be donors, acceptors ...
3 CitationsSource
#1Katarzyna Kopeć (PAN: Polish Academy of Sciences)H-Index: 5
#2Marta Pędziwiatr (PAN: Polish Academy of Sciences)H-Index: 2
Last. Joanna Grzyb (UWr: University of Wrocław)H-Index: 3
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While quantum dots (QDs) are useful as fluorescent labels, their application in biosciences is limited due to the stability and hydrophobicity of their surface. In this study, we tested two types of proteins for use as a cover for spherical QDs, composed of cadmium selenide. Pumilio homology domain (Puf), which is mostly α-helical, and leucine-rich repeat (LRR) domain, which is rich in β-sheets, were selected to determine if there is a preference for one of these secondary structure types for na...
1 CitationsSource