Da Young Kim
Hanyang University
Nuclear chemistryAbsorption (skin)NanoparticleChemistryIonic bondingHyaluronic acidAntioxidantChitosanMucoadhesionGum arabicQuercetinPermeationAbsorption (chemistry)Adhesion
2Publications
1H-index
7Citations
Publications 2
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#1Eun Suh Kim (Hanyang University)H-Index: 8
#2Da Young Kim (Hanyang University)H-Index: 1
Last. Hyeon Gyu Lee (Hanyang University)H-Index: 35
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Abstract The aim of the study was to investigate the effects of cross-linkers on quercetin (QUE) absorption characteristics of QUE-loaded chitosan nanoparticles (CS-NPs). CS-NPs (461.2–482.7 nm) were prepared by ionic gelation at pH 3.5 using tripolyphosphate (367.9 Da), dextran sulfate (>15 kDa), arabic gum (AG, >250 kDa), or hyaluronic acid (HA, >1000 kDa). Mucoadhesion and cell permeation of QUE were significantly increased by positive charged CS-NPs due to interactions with negatively charge...
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#1Eun Suh Kim (Hanyang University)H-Index: 8
#2Da Young Kim (Hanyang University)H-Index: 1
Last. Hyeon Gyu Lee (Hanyang University)H-Index: 35
view all 4 authors...
Quercetin (QUE)-loaded nanoparticles (QCG-NPs) were fabricated by ionic gelation between chitosan (CS) and gum arabic (GA) at pH 3.5. At constant CS (0.5 mg/mL) and QUE (60 μM) concentrations, QCG-NPs (260–490 nm) were prepared uniformly with 0.8–2.2 mg/mL GA and exhibited high QUE encapsulation efficiency (94.8–98.0%) and sustained QUE release (4.42–8.89% after 8 h). Because of the electrostatic interaction between QCG-NPs and the mucin layer, in vitro mucin and cell adhesion of QUE were signif...
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