R. Vijayalakshmi
Cancer Institute
Colloidal goldConjugated systemPharmacokineticsTargeted drug deliveryNuclear chemistryNanomedicineNanoparticleFourier transform infrared spectroscopyX-ray photoelectron spectroscopyChemistryBiocompatibilityDrug deliveryDrugProstate cancerDocetaxelCancer research
Publications 2
#1S. Thambiraj (University of Madras)H-Index: 6
#2R. VijayalakshmiH-Index: 1
Last. D. Ravi Shankaran (University of Madras)H-Index: 9
view all 3 authors...
Nanoformulation based drug delivery is one of the most important research areas in the field of nanomedicine, which provides promising alternatives to the limitations of conventional chemotherapy. Nano drug delivery enables improved pharmacokinetic profile, bioavailability and therapeutic efficiency compared to the regular chemotherapeutic drugs. Herein, we have established a simple method for the synthesis of docetaxel (Dtx) encapsulated poly (ethylene glycol) (PEG) functionalized gold nanopart...
4 CitationsSource
#1S. Thambiraj (University of Madras)H-Index: 6
#2S. ShruthiH-Index: 1
Last. D. Ravi Shankaran (University of Madras)H-Index: 9
view all 4 authors...
Abstract The effective use of the gold nanoparticle (AuNPs) conjugated drugs for targeted drug delivery applications is one of the most promising research areas in the field of cancer. Herein, we aimed to establish a nano drug conjugated with docetaxel as a possible therapy option. Gold nanoparticles were synthesized by chemical reduction method. This is followed by the conjugation with an anticancer drug, docetaxel (Dtx) by a non-covalent method and folic acid (FA) was conjugated by a covalent ...
11 CitationsSource