Guoqiang Hua
University of Strasbourg
PolysaccharidePromoterGeneMessenger RNASelf-healing hydrogelsEnhancerGene silencingChromatin immunoprecipitationBiomedical engineeringTranslation (biology)Gene expressionMolecular biologyRepressor3D cell cultureRegeneration (biology)SpheroidChemistryPulp (tooth)Extracellular matrixNon-coding RNAMesenchymal stem cellDentistrySmall interfering RNATranscriptional regulationTumor microenvironmentOsteoarthritisBiocompatibilityOsteosarcomaBiocompositeBiomaterialBiopolymerChitosanAngiogenesisCartilageChitinStem cellBone regenerationPersonalized medicineTranscription (biology)ChondrogenesisChemical engineeringCancer researchConnective tissuePolymerGene isoformCarcinogenesisMedicineTranscription factorBiologyScaffoldNanofiberCell biology
14Publications
3H-index
132Citations
Publications 7
Newest
#1Guoqiang Hua (UDS: University of Strasbourg)H-Index: 3
#2Henri Favreau (UDS: University of Strasbourg)
Last. Nadia Benkirane-Jessel (UDS: University of Strasbourg)H-Index: 24
view all 4 authors...
Source
#1Rana Smaida (French Institute of Health and Medical Research)H-Index: 1
#2Luc Pijnenburg (French Institute of Health and Medical Research)H-Index: 1
Last. Guoqiang Hua (UDS: University of Strasbourg)H-Index: 3
view all 10 authors...
The treatment of osteochondral defects remains a challenge. Four scaffolds were produced using Food and Drug Administration (FDA)-approved polymers to investigate their therapeutic potential for the regeneration of the osteochondral unit. Polycaprolactone (PCL) and poly(vinyl-pyrrolidone) (PVP) scaffolds were made by electrohydrodynamic techniques. Hydroxyapatite (HAp) and/or sodium hyaluronate (HA) can be then loaded to PCL nanofibers and/or PVP particles. The purpose of adding hydroxyapatite a...
1 CitationsSource
#1Guoqiang Hua (AMU: Aix-Marseille University)H-Index: 3
#2Aurélie Bergon (AMU: Aix-Marseille University)H-Index: 15
Last. Jean Imbert (AMU: Aix-Marseille University)H-Index: 30
view all 8 authors...
The presence of nuclear ERBB2 receptor-type tyrosine kinase is one of the causes of the resistance to membrane ERBB2-targeted therapy in breast cancers. It has been previously reported that this nuclear location arises through at least two different mechanisms: proteolytic shedding of the extracellular domain of the full-length receptor and translation of the messenger RNA (mRNA)-encoding ERBB2 from internal initiation codons. Here, we report a new mechanism and function where a significant port...
Source
#1Alicia Aguilar (French Institute of Health and Medical Research)H-Index: 4
#2Naimah Zein (French Institute of Health and Medical Research)H-Index: 4
Last. Guoqiang Hua (UDS: University of Strasbourg)H-Index: 3
view all 11 authors...
Chitosan is a deacetylated polysaccharide from chitin, the natural biopolymer primarily found in shells of marine crustaceans and fungi cell walls. Upon deacetylation, the protonation of free amino groups of the d-glucosamine residues of chitosan turns it into a polycation, which can easily interact with DNA, proteins, lipids, or negatively charged synthetic polymers. This positive-charged characteristic of chitosan not only increases its solubility, biodegradability, and biocompatibility, but a...
33 CitationsSource
#1Naimah Zein (French Institute of Health and Medical Research)H-Index: 4
#2Ezeddine Harmouch (French Institute of Health and Medical Research)H-Index: 2
Last. Florence Fioretti (French Institute of Health and Medical Research)H-Index: 15
view all 10 authors...
The challenge of endodontic regeneration is modulated by clinical conditions which determine five kinds of tissue requirements: pulp connective-tissue formation, dentin formation, revascularization, reinnervation and radicular edification. Polymer scaffolds constitute keystone of the different endodontic regenerative strategies. Indeed, scaffolds are crucial for carrying active molecules and competent cells which optimize the regeneration. Hydrogels are very beneficial for controlling viscosity ...
13 CitationsSource
#1Fabien Bornert (UDS: University of Strasbourg)H-Index: 11
#2Justine GantzerH-Index: 2
Last. Guoqiang Hua (UDS: University of Strasbourg)H-Index: 3
view all 5 authors...
#1Guoqiang HuaH-Index: 3
#2Bing ZhuH-Index: 1
Last. Jean Imbert (French Institute of Health and Medical Research)H-Index: 30
view all 8 authors...
Overexpression of the ERBB2 gene, linked to genomic and transcriptional amplifications, is a poor prognosis indicator in 25% to 30% of breast cancers. In contrast to some well-documented genomic amplifications, molecular mechanisms leading to ERBB2 transcriptional overexpression remain poorly characterized. Gene expression analyses of breast cancer have characterized distinct transcriptional signatures allowing a molecular classification of breast carcinoma. Coexpression of the ERBB2 and GATA4 g...
27 CitationsSource