Craig A. Erickson
Cincinnati Children's Hospital Medical Center
PsychiatryInternal medicineDevelopmental psychologyPsychologyNeurosciencePediatricsAdverse effectAutismPlaceboFragile X syndromeTolerabilityAutism spectrum disorderRisperidoneAripiprazoleIrritabilityPopulationIntellectual disabilityAnxietyClinical psychologyMedicine
153Publications
33H-index
2,991Citations
Publications 126
Newest
#1Tori L. SchaeferH-Index: 9
#2Amy A. AshworthH-Index: 1
Last. Craig A. EricksonH-Index: 33
view all 17 authors...
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#1Ernest V. Pedapati (Cincinnati Children's Hospital Medical Center)H-Index: 14
#2Lauren M. Schmitt (Cincinnati Children's Hospital Medical Center)H-Index: 11
Last. Craig A. Erickson (Cincinnati Children's Hospital Medical Center)H-Index: 33
view all 16 authors...
Fragile X Syndrome (FXS) is a monogenetic form of intellectual disability and autism in which well-established knockout (KO) animal models point to neuronal hyperexcitability and abnormal gamma-frequency physiology as a basis for key illness features. Translating these findings into patients may identify tractable treatment targets. Using a minimum norm estimate of resting state electroencephalography data, we report novel findings in FXS including: 1) increases in gamma activity across function...
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#2Randi J HagermanH-Index: 118
Last. Joseph PalumboH-Index: 17
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#1Logan K. Wink (University of Cincinnati Academic Health Center)H-Index: 15
#2Debra L. Reisinger (Cincinnati Children's Hospital Medical Center)H-Index: 4
Last. Craig A. Erickson (University of Cincinnati Academic Health Center)H-Index: 33
view all 9 authors...
Dysregulation of glutamate neurotransmission plays a critical role in autism spectrum disorder (ASD) pathophysiology and is a primary target for core deficit research treatment trials. The mechanism of action of ketamine has striking overlap with the theory of ASD as a disorder of synaptic communication and neuronal networks. This two-dose, double-blind, placebo controlled, cross-over pilot trial of intranasal (IN) ketamine targeting core social impairment included individuals with ASD (N = 21) ...
2 CitationsSource
#1Elizabeth Smith (University of Cincinnati Academic Health Center)
#2Ernest V. Pedapati (University of Cincinnati Academic Health Center)H-Index: 14
Last. Craig A. Erickson (University of Cincinnati Academic Health Center)H-Index: 33
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Abstract Electrophysiological alterations may represent a neural substrate of impaired neurocognitive processes and other phenotypic features in Fragile X Syndrome (FXS). However, the role of biological sex in electroencephalography (EEG) patterns that differentiate FXS from typical development has not been determined. This limits use of EEG in both the search for biomarkers of impairment in FXS as well as application of those markers to enhance our understanding of underlying neural mechanisms ...
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#1Makoto Miyakoshi (UCSD: University of California, San Diego)H-Index: 18
#2Lauren M. Schmitt (University of Cincinnati Academic Health Center)H-Index: 11
Last. Ernest V. Pedapati (Cincinnati Children's Hospital Medical Center)H-Index: 14
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#1Cara J. Westmark (UW: University of Wisconsin-Madison)H-Index: 16
#2Chad Kniss (UW: University of Wisconsin-Madison)H-Index: 2
Last. Elizabeth Berry-Kravis (Rush University Medical Center)H-Index: 87
view all 17 authors...
A large number of adults and children consume soy in various forms, but little information is available regarding potential neurological side effects. Prior work indicates an association between the consumption of soy-based diets and seizure prevalence in mouse models of neurological disease and in children with autism. Herein, we sought to evaluate potential associations between the consumption of soy-based formula during infancy and disease comorbidities in persons with fragile X syndrome (FXS...
2 CitationsSource
#1Michael G. Aman (OSU: Ohio State University)H-Index: 83
#2Megan Norris (OSU: Ohio State University)H-Index: 8
Last. Craig A. Erickson (Cincinnati Children's Hospital Medical Center)H-Index: 33
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Objective: The Aberrant Behavior Checklist (ABC) is a standardized rating scale used for assessing problematic behavior of individuals with developmental disabilities. It has five subscales: Irrita...
1 CitationsSource
#1Martine Lamy (Cincinnati Children's Hospital Medical Center)H-Index: 12
#2Ernest V. Pedapati (Cincinnati Children's Hospital Medical Center)H-Index: 14
Last. Craig A. Erickson (Cincinnati Children's Hospital Medical Center)H-Index: 33
view all 5 authors...
Autism spectrum disorder (ASD) is a heterogeneous neuropsychiatric condition affecting an estimated one in 36 children. Youth with ASD may have severe behavioral disturbances including irritability, aggression, and hyperactivity. Currently, there are only two medications (risperidone and aripiprazole) approved by the US Food and Drug Administration (FDA) for the treatment of irritability associated with ASD. Pharmacologic treatments are commonly used to target ASD-associated symptoms including i...
6 CitationsSource
#1Debra L. Reisinger (Cincinnati Children's Hospital Medical Center)H-Index: 4
#2Rebecca C. Shaffer (Cincinnati Children's Hospital Medical Center)H-Index: 9
Last. Craig A. Erickson (Cincinnati Children's Hospital Medical Center)H-Index: 33
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Restricted repetitive behaviors (RRBs) are a core area of impairment in autism spectrum disorder (ASD), but also affect several other neurodevelopmental disorders including fragile X syndrome (FXS). Current literature has begun to describe the RRB profile in FXS up through adolescence; however, little is known about the subtypes of RRBs in adolescents and adults. Further, literature on the RRB profile of females with FXS is limited. The present study examines the RRB profile across subtypes and ...
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