Luping Sha
Shenyang Pharmaceutical University
AnalytePharmacokineticsMass spectrometryChemistryGlycosideIn vitroIn vivoCalibration curveHeLaFormic acidAglyconeHemolysisOrbitrapHydrolysateDoxorubicin HydrochlorideChromatographyADMEAbsorption (pharmacology)Pharmacology
Publications 2
#1Miao Wang (SPU: Shenyang Pharmaceutical University)H-Index: 9
#2Da Wang (SPU: Shenyang Pharmaceutical University)H-Index: 4
Last. Zhaohua WuH-Index: 2
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: Cassane diterpenoids (CA) are considered as the main active constituents of medicinal plants belonging to the Caesalpinia genus. Three cassane derivatives, bonducellpin G (BG), 7-O-acetyl-bonducellpin C (7-O-AC) and caesalmin E (CE), isolated from Caesalpinia minax Hance seeds, showed strong anti-inflammatory activity. In this paper, pharmacokinetics (BG, 7-O-AC, CE) and tissue distribution (7-O-AC, CE) properties were studied for the first time using a reliable, sensitive and rapid UHPLC-Q-Or...
1 CitationsSource
#1Yiren Yang (SPU: Shenyang Pharmaceutical University)H-Index: 4
#2Liping Long (SPU: Shenyang Pharmaceutical University)H-Index: 3
Last. Luping Sha (SPU: Shenyang Pharmaceutical University)H-Index: 2
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Barrigenol-like triterpenoids (BATs) showed promising anti-tumor, anti-inflammatory and anti-Alzheimer's activities, while, the inhibitory strength was usually affected by their states with aglycones or glycosides. In order to find more BATs as new anti-tumor agents with much more efficiency, the chemical and pharmaceutical studies were carried out on the acid hydrolysate product (AHP) of Semen Aesculi crude extract. Thirteen BATs, including three new aglycones (1–3), two new glycosides (4, 5) a...
1 CitationsSource