Chunyang He
Intensive care medicineTraditional Chinese medicineNeuroprotectionSpinal cord injuryDiseaseParkinson's diseaseEpimedium grandiflorumIcariinNatural compoundHeterogeneous groupImportant researchActive componentCentral nervous systemTraditional medicineMedicine
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#1Chunyang HeH-Index: 2
#2Ze WangH-Index: 2
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Abstract Icariin (ICA) is a principal active component from traditional Chinese medicine Epimedium grandiflorum. To explain its traditional medical usages by modern science, a variety of pharmacological effects have been studied for ICA. In this review, we summarized the pharmacokinetics of ICA as well as its pharmacological mechanisms in neurodegenerative disease, cardiovascular disease, anti-osteoporosis, anti-inflammation, anti-oxidative stress, anti-depression and anti-tumors.
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#1Ze WangH-Index: 2
#2Chunyang HeH-Index: 2
Last. Jing-Shan ShiH-Index: 2
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: Neurodegenerative diseases are a heterogeneous group of disorders characterized by the progressive degeneration of the structure and function of the central nervous system or peripheral nervous system. Alzheimer's disease (AD), Parkinson's disease (PD) and spinal cord injury (SCI) are the common neurodegenerative diseases, which typically occur in people over the age of 60. With the rapid development of an aged society, over 60 million people worldwide are suffering from these uncurable diseas...
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